Resilient and Agile Engineering Solutions to Address Societal Challenges like Coronavirus Pandemic

Journal article


Goel, S., Hawi, S., Goel, G., Thakur, V.K., Pearce, O., Hoskins, C., Hussain, T., Agrawal, A., Upadhyaya, H., Cross, G. and Barber, A. (2020). Resilient and Agile Engineering Solutions to Address Societal Challenges like Coronavirus Pandemic. Materials Today Chemistry. https://doi.org/10.1016/j.mtchem.2020.100300
AuthorsGoel, S., Hawi, S., Goel, G., Thakur, V.K., Pearce, O., Hoskins, C., Hussain, T., Agrawal, A., Upadhyaya, H., Cross, G. and Barber, A.
Abstract

The world is witnessing tumultuous times as major economic powers including the US, UK, Russia, India, and most of Europe continue to be in a state of lockdown. The worst-hit sectors due to this lockdown are sales, production (manufacturing), transport (aerospace and automotive) and tourism. Lockdowns became necessary as a preventive measure to avoid the spread of the contagious and infectious “Coronavirus Disease 2019” (COVID-19). This newly identified disease is caused by a new strain of the virus being referred to as Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2; formerly called 2019-nCoV). We review the current medical and manufacturing response to COVID-19, including advances in instrumentation, sensing, use of lasers, fumigation chambers and development of novel tools such as lab-on-the-chip using combinatorial additive and subtractive manufacturing techniques and use of molecular modelling and molecular docking in drug and vaccine discovery. We also offer perspectives on future considerations on climate change, outsourced versus indigenous manufacturing, automation, and antimicrobial resistance. Overall, this paper attempts to identify key areas where manufacturing can be employed to address societal challenges such as COVID-19

Keywordscoronavirus, manufactruring
Year2020
JournalMaterials Today Chemistry
PublisherElsevier
Digital Object Identifier (DOI)https://doi.org/10.1016/j.mtchem.2020.100300
Web address (URL)https://www.sciencedirect.com/science/article/pii/S2468519420300604?via%3Dihub
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Print28 May 2020
Publication process dates
Accepted19 May 2020
Deposited26 May 2020
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Goel, S., Cross, G., Stukowski, A., Gamsjager, E., Beake, B. and Agrawal, A. (2018). Designing nanoindentation simulation studies by appropriate indenter choices: Case study on single crystal tungsten. Computational Materials Science. 152, pp. 196-210. https://doi.org/https://doi.org/10.1016/j.commatsci.2018.04.044
Hydration dependent mechanical performance of denture adhesive hydrogels
Zhang, F, An, Y, Roohpour, N, Barber, AH and Gautrot, JE (2018). Hydration dependent mechanical performance of denture adhesive hydrogels. Dental Materials. 34 (10), pp. 1440-1448. https://doi.org/10.1016/j.dental.2018.06.015
Approaches to 3D printing teeth from X-ray microtomography.
Cresswell-Boyes, AJ, Barber, AH, Mills, D, Tatla, A and Davis, GR (2018). Approaches to 3D printing teeth from X-ray microtomography. Journal of Microscopy. 272 (3), pp. 207-212. https://doi.org/10.1111/jmi.12725
Optimization of digital volume correlation computation in SR-microCT images of trabecular bone and bone-biomaterial systems.
Peña Fernández, M, Barber, AH, Blunn, GW and Tozzi, G (2018). Optimization of digital volume correlation computation in SR-microCT images of trabecular bone and bone-biomaterial systems. Journal of Microscopy. 272 (3), pp. 213-272. https://doi.org/10.1111/jmi.12745
Development of sustainable biodegradable lignocellulosic hemp fiber/ polycaprolactone biocomposites for light weight applications
Barber, AH, Dhakal, HN, Ismail, S, Zhang, Z, Welsh, E, Maigret, J-E and Beaugrand, J (2018). Development of sustainable biodegradable lignocellulosic hemp fiber/ polycaprolactone biocomposites for light weight applications. Composites Part A: Applied Science and Manufacturing. 113, pp. 350-358. https://doi.org/10.1016/j.compositesa.2018.08.005
Preservation of bone tissue integrity with temperature control for in situ SR-MicroCT experiments
Fernández, MP, Dall'Ara, E, Kao, AP, Bodey, AJ, Karali, A, Blunn, GW, Barber, AH and Tozzi, G (2018). Preservation of bone tissue integrity with temperature control for in situ SR-MicroCT experiments. Materials. 11 (11). https://doi.org/10.3390/ma11112155
Effect of SR-microCT radiation on the mechanical integrity of trabecular bone using in situ mechanical testing and digital volume correlation
Peña Fernández, M, Cipiccia, S, Dall'Ara, E, Bodey, AJ, Parwani, R, Pani, M, Blunn, GW, Barber, AH and Tozzi, G (2018). Effect of SR-microCT radiation on the mechanical integrity of trabecular bone using in situ mechanical testing and digital volume correlation. Journal of the Mechanical Behavior of Biomedical Materials. 88, pp. 109-119. https://doi.org/10.1016/j.jmbbm.2018.08.012
Micro-mechanical properties of the tendon-to-bone attachment
Deymier, AC, An, Y, Boyle, JJ, Schwartz, AG, Birman, V, Genin, GM, Thomopoulos, S and Barber, AH (2017). Micro-mechanical properties of the tendon-to-bone attachment. Acta Biomaterialia. 56, pp. 25-35. https://doi.org/10.1016/j.actbio.2017.01.037
Surface free energy analysis of electrospun fibers based on Rayleigh-Plateau/Weber instabilities
Stachewicz, U, Dijksman, JF, Soudani, C, Tunnicliffe, LB, Busfield, JJC and Barber, AH (2017). Surface free energy analysis of electrospun fibers based on Rayleigh-Plateau/Weber instabilities. European Polymer Journal. 91, pp. 368-375. https://doi.org/10.1016/j.eurpolymj.2017.04.017
Extreme Toughness Exhibited in Electrospun Polystyrene Fibers
Zhang, F and Barber, AH (2017). Extreme Toughness Exhibited in Electrospun Polystyrene Fibers. Macromolecular Materials and Engineering. 302 (9), pp. 1700084-1700084. https://doi.org/10.1002/mame.201700084
X-ray Imaging of Transplanar Liquid Transport Mechanisms in Single Layer Textiles
Zhang, G, Parwani, R, Stone, CA, Barber, AH and Botto, L (2017). X-ray Imaging of Transplanar Liquid Transport Mechanisms in Single Layer Textiles. Langmuir. 33 (43), pp. 12072-12079. https://doi.org/10.1021/acs.langmuir.7b02982
Stress concentrations in nanoscale defective graphene
Wang, C, Wang, J and Barber, AH (2017). Stress concentrations in nanoscale defective graphene. AIP Advances. 7 (11), pp. 115001-115001. https://doi.org/10.1063/1.4996387
Investigating the emission characteristics of single crystal YAG when activated by high power laser beams
Salimian, A, Silver, J, Fern, GR, Upadhyaya, H, Metcalfe, A, Ireland, TG, Harris, P and Haghpanahan, R (2016). Investigating the emission characteristics of single crystal YAG when activated by high power laser beams. ECS Journal of Solid State Science and Technology. 5 (10), pp. R172-R177. https://doi.org/10.1149/2.0271610jss
Laser diode induced lighting modules
Salimian, A., Fern, G.R., Upadhyaya, H. and Silver, J. (2016). Laser diode induced lighting modules. ECS Journal of Solid State Science and Technology. 5 (3), pp. R26-R33. https://doi.org/10.1149/2.0101603jss
Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility
Theocharidis, G, Drymoussi, Z, Kao, AP, Barber, AH, Lee, DA, Braun, KM and Connelly, JT (2016). Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility. Journal of Investigative Dermatology. 136 (1), pp. 74-83. https://doi.org/10.1038/JID.2015.352
Evaluation of bioprosthetic heart valve failure using a matrix-fibril shear stress transfer approach
Anssari-Benam, A, Barber, AH and Bucchi, A (2016). Evaluation of bioprosthetic heart valve failure using a matrix-fibril shear stress transfer approach. Journal of Materials Science: Materials in Medicine. 27 (2). https://doi.org/10.1007/s10856-015-5657-2
Failure mechanisms in denture adhesives
An, Y, Li, D, Roohpour, N, Gautrot, JE and Barber, AH (2016). Failure mechanisms in denture adhesives. Dental Materials. 32 (5), pp. 615-623. https://doi.org/10.1016/j.dental.2016.01.007
Morphological and Mechanical Biomimetic Bone Structures
Parwani, R, Curto, M, Kao, AP, Rowley, PJ, Pani, M, Tozzi, G and Barber, AH (2016). Morphological and Mechanical Biomimetic Bone Structures. ACS Biomaterials Science & Engineering. 3 (11), pp. 2761-2767. https://doi.org/10.1021/acsbiomaterials.6b00652
High mobility titanium-doped indium oxide for use in tandem solar cells deposited via pulsed DC magnetron sputtering
Grew, B, Bowers, JW, Lisco, F, Arnou, N, Walls, JM and Upadhyaya, HM (2014). High mobility titanium-doped indium oxide for use in tandem solar cells deposited via pulsed DC magnetron sputtering. Energy Procedia. 60 (C), pp. 148-155. https://doi.org/10.1016/j.egypro.2014.12.357
Design and optimisation of process parameters in an in-line CIGS evaporation pilot system
Wei, Z., Bobbili, P.R., Senthilarasu, S., Shimell, T. and Upadhyaya, H.M. (2014). Design and optimisation of process parameters in an in-line CIGS evaporation pilot system. Surface & Coatings Technology. 241, pp. 159-167. https://doi.org/10.1016/j.surfcoat.2013.10.033
Spray deposited copper zinc tin sulphide (Cu<inf>2</inf>ZnSnS<inf>4</inf>) film as a counter electrode in dye sensitized solar cells
Swami, S.K., Chaturvedi, N., Kumar, A., Chander, N., Dutta, V., Kumar, D.K., Ivaturi, A., Senthilarasu, S. and Upadhyaya, H.M. (2014). Spray deposited copper zinc tin sulphide (Cu<inf>2</inf>ZnSnS<inf>4</inf>) film as a counter electrode in dye sensitized solar cells. Physical Chemistry Chemical Physics. 16 (43), pp. 23993-23999. https://doi.org/10.1039/c4cp03312d