Structural orientation dependent sub-lamellar bone mechanics

Journal article

Jimenez-Palomar, I, Shipov, A, Shahar, R and Barber, AH (2015). Structural orientation dependent sub-lamellar bone mechanics. Journal of the Mechanical Behavior of Biomedical Materials. 52, pp. 63-71. https://doi.org/10.1016/j.jmbbm.2015.02.031
AuthorsJimenez-Palomar, I, Shipov, A, Shahar, R and Barber, AH
Abstract

The lamellar unit is a critical component in defining the overall mechanical properties of bone. In this paper, micro-beams of bone with dimensions comparable to the lamellar unit were fabricated using focused ion beam (FIB) microscopy and mechanically tested in bending to failure using atomic force microscopy (AFM). A variation in the mechanical properties, including elastic modulus, strength and work to fracture of the micro-beams was observed and related to the collagen fibril orientation inferred from back-scattered scanning electron microscopy (SEM) imaging. Established mechanical models were further applied to describe the relationship between collagen fibril orientation and mechanical behaviour of the lamellar unit. Our results highlight the ability to measure mechanical properties of discrete bone volumes directly and correlate with structural orientation of collagen fibrils.

Keywords0903 Biomedical Engineering; 0912 Materials Engineering; 0913 Mechanical Engineering; Biomedical Engineering
Year2015
JournalJournal of the Mechanical Behavior of Biomedical Materials
Journal citation52, pp. 63-71
ISSN1751-6161
Digital Object Identifier (DOI)https://doi.org/10.1016/j.jmbbm.2015.02.031
Publication dates
Print09 Mar 2015
Publication process dates
Deposited21 Aug 2018
Accepted28 Feb 2015
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