A pre-post pilot study of electronic cigarettes to reduce smoking in people with severe mental illness
Journal article
Hickling, L, Perez-Iglesias, R, McNeil, A, Dawkins, LE, Moxham, J, Ruffell, T, Sendt, K-V and McQuire, P (2018). A pre-post pilot study of electronic cigarettes to reduce smoking in people with severe mental illness. Psychological Medicine. 49 (6), pp. 1033-1040. https://doi.org/10.1017/S0033291718001782
| Authors | Hickling, L, Perez-Iglesias, R, McNeil, A, Dawkins, LE, Moxham, J, Ruffell, T, Sendt, K-V and McQuire, P |
|---|---|
| Abstract | Background: Smoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses (SMI). The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population. Method: Fifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales. Results: There was a significant (≥50%) reduction in cigarettes consumed per day between baseline and week 6 (F(2.596,116.800)=25.878,p<0.001), and e-cigarette use was stable during this period (F(2.932,46.504)=2.023,p=0.115). These changes were verified by significant carbon monoxide reductions between these time points (F(3.335,126.633)=5.063),p=0.002). Conclusions: The provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder. |
| Keywords | psychosis; schizophrenia; tobacco; smoking; e-cigarette; electronic cigarette; harm reduction; acceptability; 1701 Psychology; 1117 Public Health And Health Services; 1109 Neurosciences; Psychiatry |
| Year | 2018 |
| Journal | Psychological Medicine |
| Journal citation | 49 (6), pp. 1033-1040 |
| Publisher | Cambridge University Press (CUP) |
| ISSN | 0033-2917 |
| Digital Object Identifier (DOI) | https://doi.org/10.1017/S0033291718001782 |
| https://doi.org/10.1017/S0033291718001782 | |
| Publication dates | |
| 10 Jul 2018 | |
| Publication process dates | |
| Deposited | 22 Jun 2018 |
| Accepted | 14 Jun 2018 |
| Accepted author manuscript | License File Access Level Open |
| Supplemental file | License File Access Level Open |
| Supplemental file | License File Access Level Open |
| Supplemental file | License File Access Level Open |
| Supplemental file | License |
| Supplemental file | License File Access Level Open |
Permalink -
https://openresearch.lsbu.ac.uk/item/86q25
Download files
Accepted author manuscript
| Manuscript Final 3 (clean).docx | ||
| License: CC BY 4.0 | ||
| File access level: Open | ||
Supplemental file
| Table 1.docx | ||
| License: CC BY 4.0 | ||
| File access level: Open | ||
| Table 2.docx | ||
| License: CC BY 4.0 | ||
| File access level: Open | ||
| Fig 1 tif image.tif | ||
| License: CC BY 4.0 | ||
| File access level: Open | ||
| Fig 2 TIFF v.3.1.tif | ||
| License: CC BY 4.0 | ||
| Fig 3 TIFF v.3.tif | ||
| License: CC BY 4.0 | ||
| File access level: Open | ||
256
total views383
total downloads0
views this month2
downloads this month
Export as
Related outputs
Change in vaping, smoking and dual use identities predicts quit success and cigarette usage: A prospective study of people quitting smoking with electronic cigarette support
Frings, D., Albery, I., Kimber, C., Naughton, F., Sideropoulos, V. and Dawkins, L. (2024). Change in vaping, smoking and dual use identities predicts quit success and cigarette usage: A prospective study of people quitting smoking with electronic cigarette support. British Journal of Health Psychology. https://doi.org/10.1111/bjhp.12735Interventions for Quitting Vaping
Butler, A., Lindson, N., Livingstone-Banks, J., Notley, C., Turner, T., Rigotti, N., Fanshawe, T.R., Dawkins, L. and Hartmann-Boyce, J. (2024). Interventions for Quitting Vaping. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD016058Young People’s use of Disposable Vapes: A Qualitative Study
Notley, C, Varley, A, Pope, I, Dawkins, L. and Ward, E (2024). Young People’s use of Disposable Vapes: A Qualitative Study. Addiction. https://doi.org/10.1111/add.16570SRNT Europe Debate: The use of nicotine oral products in adults may be a rationale behaviour
Dawkins, L. and Hall, W. (2024). SRNT Europe Debate: The use of nicotine oral products in adults may be a rationale behaviour. Nicotine and Tobacco Research. https://doi.org/10.1093/ntr/ntae029
Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions
Kimber, C., Frings, D., Albery, I., Cox, S. and Dawkins, L. (2023). Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions. London South Bank University. https://doi.org/10.18744/lsbu.95y88Examining acute psychopharmacological effects of nicotine vaping versus heated tobacco products in a randomised crossover study of product naive adult smokers
Kale, D., Tattan- Birch, H., Brown, J., Cox, S., Dawkins, L., Goniewicz, M., Morris, K. and Shahab, L. (2023). Examining acute psychopharmacological effects of nicotine vaping versus heated tobacco products in a randomised crossover study of product naive adult smokers. Scientific Reports. 13 (22676). https://doi.org/10.1038/s41598-023-49602-3Comparing identity, attitudes, and indicators of effectiveness in people who smoke, vape or use heated tobacco products: a cross-sectional study
Kale, D, Brown, J., Dawkins, L., Goniewicz, M., Leppin, C, Tattan-Birch, H and Shahab, L. (2023). Comparing identity, attitudes, and indicators of effectiveness in people who smoke, vape or use heated tobacco products: a cross-sectional study . Addictive Behaviors. 151, p. 107933. https://doi.org/10.1016/j.addbeh.2023.107933Mobile Phone Text Messages to Support People to Stop Smoking by Switching to Vaping: Codevelopment, Coproduction, and Initial Testing Study.
Sideropoulos, V., Vangeli, E., Naughton, F., Cox, S., Frings, D., Notley, C., Brown, J., Kimber, C. and Dawkins, L. (2023). Mobile Phone Text Messages to Support People to Stop Smoking by Switching to Vaping: Codevelopment, Coproduction, and Initial Testing Study. JMIR Formative Research. 7, p. e49668. https://doi.org/10.2196/49668Square Pegs, Round Holes: Issues and considerations from running a cluster Randomised Control Trial in people who smoke and experience homelessness
Soar, K., Mair, C., Cox, S. and Dawkins, L. (2023). Square Pegs, Round Holes: Issues and considerations from running a cluster Randomised Control Trial in people who smoke and experience homelessness. Society for Research on Nicotine and Tobacco. Oslo 17 - 21 Sep 2019Lessons learnt from Project SCeTCH: a multi-centre cluster randomised controlled trial evaluating the effectiveness of e-cigarettes compared with usual care for smoking cessation in those accessing homeless services
Soar, K., Cox, S. and Dawkins, L. (2023). Lessons learnt from Project SCeTCH: a multi-centre cluster randomised controlled trial evaluating the effectiveness of e-cigarettes compared with usual care for smoking cessation in those accessing homeless services . Smoking Cessation and Health. Manchester 14 - 14 Sep 2023Mobile phone text messages to support people to stop smoking by switching to vaping: co-development, co-production, and initial testing
Sideropoulos, V., Vangeli, E., Naughton, F., Cox, S., Frings, D., Notley, C., Brown, J., Kimber, C. and Dawkins, L. (2023). Mobile phone text messages to support people to stop smoking by switching to vaping: co-development, co-production, and initial testing. JMIR Formative Research.E‐cigarette support for smoking cessation: Identifying the effectiveness of intervention components in an on‐line randomized optimization experiment
Kimber, C., Sideropoulos, V., Cox, S., Frings, D., Naughton, F., Brown, J., McRobbie, H. and Dawkins, L. (2023). E‐cigarette support for smoking cessation: Identifying the effectiveness of intervention components in an on‐line randomized optimization experiment. Addiction (Abingdon, England). 118 (11), pp. 2105-2117. https://doi.org/10.1111/add.16294Medicalisation of vaping in the UK? E-cigarette users' perspectives on the merging of commercial and medical routes to vaping
Ward, E., Dawkins, L., Holland, R., Pope, I. and Notley, C. (2023). Medicalisation of vaping in the UK? E-cigarette users' perspectives on the merging of commercial and medical routes to vaping. Perspectives in Public Health. https://doi.org/10.1177/17579139231185481E-cigarette support for smoking cessation: Identifying the effectiveness of intervention components in an online randomised optimisation trial
Dawkins, L. and Kimber, C. (2023). E-cigarette support for smoking cessation: Identifying the effectiveness of intervention components in an online randomised optimisation trial. London South Bank University. https://doi.org/10.18744/lsbu.92xq8Is e-cigarette use associated with persistence or discontinuation of combustible cigarettes? A 24-month longitudinal investigation in young adult binge drinkers.
Martinez-Loredo, V., González-Roz, Alba, Dawkins, L., Singh, Desmond, Murphy, James G and MacKillop, J. (2022). Is e-cigarette use associated with persistence or discontinuation of combustible cigarettes? A 24-month longitudinal investigation in young adult binge drinkers. Nicotine & Tobacco Research. https://doi.org/6530318Effects of e-cigarettes vs usual care for smoking cessation when offered at homeless centres: protocol for a cluster randomised controlled trial.
Soar, K., Mair, C., Dawkins, L., Bauld, L., Brown, R., Lennon, J, Ford, A., McMillan, L, Hajek, P., Li, J., Parrott, S., Notley, C., Ward, E' Varley, A, Robson, D., Pesola, F., Tyler, A., Carlisle, M and Dr Sharon Cox (2022). Effects of e-cigarettes vs usual care for smoking cessation when offered at homeless centres: protocol for a cluster randomised controlled trial. London Network of Nurses and Midwives Homelessness Annual Conference. St Martins in the Field, London 01 - 01 Apr 2022Comparing the Effects of the EU- Versus the US-JUUL Pod in a Sample of UK Smokers: Nicotine Absorption, Satisfaction, and Other Nicotine-Related Subjective Effects
Kimber, C., Zaidell, L., Hunter, S., Cox, S., Notley, C. and Dawkins, L. (2022). Comparing the Effects of the EU- Versus the US-JUUL Pod in a Sample of UK Smokers: Nicotine Absorption, Satisfaction, and Other Nicotine-Related Subjective Effects. Nicotine & Tobacco Research. https://doi.org/10.1093/ntr/ntac289Cutting down, quitting and motivation to stop smoking by self-reported COVID-19 status: Representative cross-sectional surveys in England.
Cox, S., Tattan-Birch, H., Jackson, S., Dawkins, L., Brown, J. and Shahab, L. (2022). Cutting down, quitting and motivation to stop smoking by self-reported COVID-19 status: Representative cross-sectional surveys in England. Addiction (Abingdon, England). https://doi.org/10.1111/add.16029Evaluating the effectiveness of e‐cigarettes compared with usual care for smoking cessation when offered to smokers at homeless centres: Protocol for a multi‐centre cluster randomised controlled trial in Great Britain
Cox, S., Bauld, Linda, Brown, R., Carlise, M., Ford, A., Hajek, P., Li, J., Notley, C., Parrott, S., Pesola, F., Robson, D., Soar, K., Tyler, A., Ward, E. and Dawkins, L. (2022). Evaluating the effectiveness of e‐cigarettes compared with usual care for smoking cessation when offered to smokers at homeless centres: Protocol for a multi‐centre cluster randomised controlled trial in Great Britain. Addiction (Abingdon, England). https://doi.org/10.1111/add.15851Water Consumption Increases Handwriting Speed andVolume Consumed Relates to Increased Finger‑tapping Speed in Schoolchildren
Booth, P., Hunyadvari, N., Dawkins, L., Moore, D., Gentile-Rapinett, G. and Edmonds, C,J. (2021). Water Consumption Increases Handwriting Speed andVolume Consumed Relates to Increased Finger‑tapping Speed in Schoolchildren. Journal of Cognitive Enhancement. https://doi.org/10.1007/s41465-021-00232-5Dataset: Co-development of mobile phone text messages to support smokers’ quitting by switching to an e-cigarette
Sideropoulos, V., Vangeli, E., Naughton, F, Cox, S., Frings, D., Notley, C., Brown, J., Kimber, C. and Dawkins, L. (2021). Dataset: Co-development of mobile phone text messages to support smokers’ quitting by switching to an e-cigarette. London South Bank University. https://doi.org/10.18744/lsbu.8y92zDevelopment and Testing of Relative Risk-based Health Messages for Electronic Cigarette Products
Kimber, C., Cox, S., Frings, D., Albery, I. and Dawkins, L. (2021). Development and Testing of Relative Risk-based Health Messages for Electronic Cigarette Products. Harm Reduction Journal. 18 (96). https://doi.org/10.1186/s12954-021-00540-1Study protocol for Testing Nicotine Pod Vaping Devices: Are EU-TPD (Tobacco Product Directive) compliant pod-devices sufficiently satisfying to UK smokers?
Kimber, C., Cox, S., Notley, C., Hunter, S., Zaidell, L. and Dawkins, L. (2021). Study protocol for Testing Nicotine Pod Vaping Devices: Are EU-TPD (Tobacco Product Directive) compliant pod-devices sufficiently satisfying to UK smokers? In-principle acceptance in Nicotine and Tobacco Research. https://doi.org/10.17605/OSF.IO/D5N2VExploration of the physical health of dual users of heroin and crack in methadone treatment who inject or have previously injected drugs
Heidebrecht, F., Macleod, M.B. and Dawkins, L. (2021). Exploration of the physical health of dual users of heroin and crack in methadone treatment who inject or have previously injected drugs. Heroin Addiction And Related Clinical Problems.Changes in puffing topography and subjective effects over a 2-week period in e-cigarette naïve smokers: effects of device type and nicotine concentrations
Kimber, C., Soar, K. and Dawkins, L. (2021). Changes in puffing topography and subjective effects over a 2-week period in e-cigarette naïve smokers: effects of device type and nicotine concentrations. Addictive Behaviors. 118, p. 106909. https://doi.org/10.1016/j.addbeh.2021.106909Does the content and source credibility of health and risk messages related to nicotine vaping products have an impact on harm perception and behavioural intentions? A systematic review
Erku, D., Bauld, L., Dawkins, L., Gartner, C., Steadman, K., Noar, S., Shrestha, S. and Morphett, K. (2021). Does the content and source credibility of health and risk messages related to nicotine vaping products have an impact on harm perception and behavioural intentions? A systematic review. Addiction. 116 (12), pp. 3290-3303. https://doi.org/10.1111/add.15473Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers
Rycroft, N., Hogarth, L., MacKillop, J. and Dawkins, L. (2020). Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers. Addictive Behaviors. 115, p. 106737. https://doi.org/10.1016/j.addbeh.2020.106737User pathways of e‐cigarette use to support long term tobacco smoking relapse prevention: a qualitative analysis
Notley, C., Ward, E., Dawkins, L. and Holland, R. (2020). User pathways of e‐cigarette use to support long term tobacco smoking relapse prevention: a qualitative analysis. Addiction (Abingdon, England). 116 (3), pp. 596-605. https://doi.org/10.1111/add.15226Exploring the uptake and use of electronic cigarettes provided to smokers accessing homeless centres: a four-centre cluster feasibility study
Cox, S., Ford, A., Li, Ji., Best, C., Tyler, A., Robson, D., Bauld, L., Hajek, P., Uny, I., Parrott, S. and Dawkins, L. (2020). Exploring the uptake and use of electronic cigarettes provided to smokers accessing homeless centres: a four-centre cluster feasibility study. Journal of Public Health Research. 9 (7). https://doi.org/10.3310/phr09070Study protocol for comparing the subjective effects and nicotine delivery associated with the use of the EU and the US JUUL pod vaping device in UK smokers
Kimber, C., Cox, S., Caitlin, N., Hunter, S., Zaidell, L. and Dawkins, L. (2020). Study protocol for comparing the subjective effects and nicotine delivery associated with the use of the EU and the US JUUL pod vaping device in UK smokers. Nicotine and Tobacco Research (OUP). https://doi.org/10.17605/OSF.IO/5J3EWA cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain
Dawkins, L., Bauld, L., Ford, A., Robson, D., Hajek, P., Parrott, S., Best, C., Li, J., Tyler, A., Uny, I. and Cox, S. (2020). A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain. PLoS ONE. https://doi.org/10.1371/journal.pone.0240968Responsibility, normalisation and negotiations of harm: E-cigarette users' opinions and experiences of vaping around children
Ward, E., Dawkins, L., Holland, R. and Notley, C. (2020). Responsibility, normalisation and negotiations of harm: E-cigarette users' opinions and experiences of vaping around children. International Journal of Drug Policy. 88, p. 103016. https://doi.org/10.1016/j.drugpo.2020.103016Reported patterns of vaping to support long-term abstinence from smoking: a cross-sectional survey of a convenience sample of vapers
Gentry, S., Ward, E., Dawkins, L., Holland, R. and Notley, C. (2020). Reported patterns of vaping to support long-term abstinence from smoking: a cross-sectional survey of a convenience sample of vapers. Harm Reduction Journal. 17, p. 70. https://doi.org/10.1186/s12954-020-00418-8Data for: A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain
Dawkins, L., Cox, S., Tyler, A., Bauld, L, Ford, A, Robson, D, Hajek, P, Best, C, Li, J, Uny, I and Parrott, S (2020). Data for: A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain. London South Bank University. https://doi.org/10.18744/lsbu.8q255A qualitative exploration of consumers’ perceived impacts, behavioural reactions, and future reflections of the EU Tobacco Products Directive (2017) as applied to electronic cigarettes
Ward, E, Anholt, C, Gentry, S, Dawkins, L, Holland, R and Notely, C (2020). A qualitative exploration of consumers’ perceived impacts, behavioural reactions, and future reflections of the EU Tobacco Products Directive (2017) as applied to electronic cigarettes. Tobacco Use Insights. 13, pp. 1-9. https://doi.org/10.1177/1179173X20925458Daily exposure to formaldehyde and acetaldehyde and potential health risk associated with use of high and low nicotine e-liquid concentrations
Kosmider, L, Cox, S, Marzena, Z, Jolanta, K, Goniewicz, M, McRobbie, H, Kimber, C and Dawkins, L (2020). Daily exposure to formaldehyde and acetaldehyde and potential health risk associated with use of high and low nicotine e-liquid concentrations. Scientific Reports. 10 (6546). https://doi.org/10.1038/s41598-020-63292-1Smoking amongst adults experiencing homelessness: A systematic review of prevalence rates, interventions and the barriers and facilitators to quitting and staying quit
Soar, K., Dawkins, L., Robson, D. and Cox, S. (2020). Smoking amongst adults experiencing homelessness: A systematic review of prevalence rates, interventions and the barriers and facilitators to quitting and staying quit. Journal of Smoking Cessation. 15 (2), pp. 94-108. https://doi.org/10.1017/jsc.2020.11Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions.
Kimber, C., Frings, D., Cox, S., Albery, I. and Dawkins, L. (2020). Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions. Addictive Behaviors. 101, p. 106177. https://doi.org/10.1016/j.addbeh.2019.106177E-cigarettes compared with nicotine replacement therapy within the UK stop smoking services: The TEC RCT
Hajek, P, Phillips-Waller, A, Przulj, D, Pesola, F, Smith, KM, Bisal, N, Li, J, Parrott, S, Sasieni, P, Dawkins, L, Ross, L, Goniewicz, M, Wu, Q and McRobbie, HJ (2019). E-cigarettes compared with nicotine replacement therapy within the UK stop smoking services: The TEC RCT. Health Technology Assessment. 23 (43), pp. vii-81. https://doi.org/10.3310/hta23430A systematic review of smoking, smoking cessation and the homeless: there is a will but is there a way?
Cox, S., Dawkins, L., Robson, D. and Soar, K. (2019). A systematic review of smoking, smoking cessation and the homeless: there is a will but is there a way? Lisbon Addictions Conference 2019. Lisbon 09 - 11 Oct 2019Investigating within-person patterns and trajectories of dual e-cigarette and tobacco use: the TRAJECT mixed methods study protocol
Cox, S., Notley, C., Dawkins, L., Naughton, F., Beard, E., Kimber, C., Ward, E., Holland, R. and Kwasnicka, D. (2019). Investigating within-person patterns and trajectories of dual e-cigarette and tobacco use: the TRAJECT mixed methods study protocol. Society for Research on Nicotine and Tobacco. Oslo 17 - 21 Sep 2019Cost-effectiveness of e-cigarettes compared with nicotine replacement therapy in stop smoking services in England (TEC study): a randomised controlled trial
Li, J., Hajek, P., Pesola, F., Wu, Q., Phillips-Waller, A., Przuli, D., Myers Smith, K., Bisal, N., Sasieni, P., Dawkins, L., Ross, L., Goniewicz, M., McRobbie, H. and Parrott, S. (2019). Cost-effectiveness of e-cigarettes compared with nicotine replacement therapy in stop smoking services in England (TEC study): a randomised controlled trial. Addiction. 115 (3), pp. 507-517. https://doi.org/10.1111/add.14829