Nicotine absorption from e-cigarettes over 12 months
Journal article
Soar, K, Kimber, CF, McRobbie, H and Dawkins, LE (2018). Nicotine absorption from e-cigarettes over 12 months. Addictive Behaviors. 91, pp. 102-105. https://doi.org/10.1016/j.addbeh.2018.07.019
| Authors | Soar, K, Kimber, CF, McRobbie, H and Dawkins, LE |
|---|---|
| Abstract | Background: Research indicates that, over time, exclusive e-cigarette users (vapers) gradually reduce the nicotine concentration in their e-liquid and transition to more sophisticated devices. Alongside this, consumption of e-liquid increases and constant cotinine levels are maintained. Aims: We aimed to confirm these observations in 27 experienced vapers tested at baseline and 12 months later, by measuring nicotine absorption (via salivary levels of the nicotine metabolite cotinine; ng/ml), nicotine concentrations in e-liquid (mg/mL), volume of e-liquid consumed (mL per day), device types and flavours used, both at baseline and 12 months. Results: Vapers reduced both their nicotine concentrations in e-liquid over 12 months (from 13.83 mg/mL at baseline to 9.91 at follow up) but significantly increased their e-liquid consumption (from 4.44 to 6.84 mL). No significant changes in salivary cotinine concentrations (370.88 ng/mL at baseline and 415.78 ng/mL at follow up) were observed. There was an increase in sub-ohming (using an atomiser coil with resistance of < 1 ohm with increased power) at 12 months, and in the use of fruit flavoured e-liquids. Conclusions: Our sample of experienced vapers reduced the concentration of nicotine in their e-liquid over time, but maintained their nicotine intake possibly through self-titration via more intensive puffing. Findings suggest there may be little benefit in reducing nicotine e-liquid concentration since this appears to result in higher e-liquid consumption which may incur both a financial and health cost. Gaining an understanding of underlying reasons for lowering e-liquid concentration would be a useful line of empirical enquiry. |
| Keywords | e-cigarettes; cotinine; nicotine absorption; vapers; nicotine concentrations; titration; 1701 Psychology; Substance Abuse |
| Year | 2018 |
| Journal | Addictive Behaviors |
| Journal citation | 91, pp. 102-105 |
| Publisher | Elsevier |
| ISSN | 1873-6327 |
| Digital Object Identifier (DOI) | https://doi.org/10.1016/j.addbeh.2018.07.019 |
| Publication dates | |
| 21 Jul 2018 | |
| Publication process dates | |
| Deposited | 23 Jul 2018 |
| Accepted | 20 Jul 2018 |
| Accepted author manuscript | File Access Level Open |
Permalink -
https://openresearch.lsbu.ac.uk/item/869zy
Download files
51
total views61
total downloads1
views this month1
downloads this month
Export as
Related outputs
The Time Course of Compensatory Puffing With an Electronic Cigarette: Secondary Analysis of Real-World Puffing Data With High and Low Nicotine Concentration Under Fixed and Adjustable Power Settings
Cox, S., Goniewicz, M., Kosmider, Leon, McRobbie, H., Kimber, C. and Dawkins, Lynne (2021). The Time Course of Compensatory Puffing With an Electronic Cigarette: Secondary Analysis of Real-World Puffing Data With High and Low Nicotine Concentration Under Fixed and Adjustable Power Settings. Nicotine & Tobacco Research. https://doi.org/10.1093/ntr/ntab013Study protocol for Testing Nicotine Pod Vaping Devices: Are EU-TPD (Tobacco Product Directive) compliant pod-devices sufficiently satisfying to UK smokers?
Kimber, C., Cox, S., Notley, C., Hunter, S., Zaidell, L. and Dawkins, L. (2021). Study protocol for Testing Nicotine Pod Vaping Devices: Are EU-TPD (Tobacco Product Directive) compliant pod-devices sufficiently satisfying to UK smokers? In-principle acceptance in Nicotine and Tobacco Research. https://doi.org/10.17605/OSF.IO/D5N2VExploration of the physical health of dual users of heroin and crack in methadone treatment who inject or have previously injected drugs
Heidebrecht, F., Macleod, M.B. and Dawkins, L. (2021). Exploration of the physical health of dual users of heroin and crack in methadone treatment who inject or have previously injected drugs. Heroin Addiction And Related Clinical Problems.Changes in puffing topography and subjective effects over a 2-week period in e-cigarette naïve smokers: effects of device type and nicotine concentrations
Kimber, C., Soar, K. and Dawkins, L. (2021). Changes in puffing topography and subjective effects over a 2-week period in e-cigarette naïve smokers: effects of device type and nicotine concentrations. Addictive Behaviors. 118, p. 106909. https://doi.org/10.1016/j.addbeh.2021.106909Does the content and source credibility of health and risk messages related to nicotine vaping products have an impact on harm perception and behavioural intentions? A systematic review
Erku, D., Bauld, L., Dawkins, L., Gartner, C., Steadman, K., Noar, S., Shrestha, S. and Morphett, K. (2021). Does the content and source credibility of health and risk messages related to nicotine vaping products have an impact on harm perception and behavioural intentions? A systematic review. Addiction. https://doi.org/10.1111/add.15473Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers
Rycroft, N., Hogarth, L., MacKillop, J. and Dawkins, L. (2020). Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers. Addictive Behaviors. 115, p. 106737. https://doi.org/10.1016/j.addbeh.2020.106737User pathways of e‐cigarette use to support long term tobacco smoking relapse prevention: a qualitative analysis
Notley, C., Ward, E., Dawkins, L. and Holland, R. (2020). User pathways of e‐cigarette use to support long term tobacco smoking relapse prevention: a qualitative analysis. Addiction (Abingdon, England). 116 (3), pp. 596-605. https://doi.org/10.1111/add.15226Exploring the uptake and use of electronic cigarettes provided to smokers accessing homeless centres: a four-centre cluster feasibility study
Cox, S., Ford, A., Li, Ji., Best, C., Tyler, A., Robson, D., Bauld, L., Hajek, P., Uny, I., Parrott, S. and Dawkins, L. (2020). Exploring the uptake and use of electronic cigarettes provided to smokers accessing homeless centres: a four-centre cluster feasibility study. Journal of Public Health Research.Study protocol for comparing the subjective effects and nicotine delivery associated with the use of the EU and the US JUUL pod vaping device in UK smokers
Kimber, C., Cox, S., Caitlin, N., Steve, H., Zaidell, L. and Dawkins, L. (2020). Study protocol for comparing the subjective effects and nicotine delivery associated with the use of the EU and the US JUUL pod vaping device in UK smokers. Nicotine and Tobacco Research (OUP). https://doi.org/10.17605/OSF.IO/5J3EWA cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain
Dawkins, L., Bauld, L., Ford, A., Robson, D., Hajek, P., Parrott, S., Best, C., Li, J., Tyler, A., Uny, I. and Cox, S. (2020). A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain. PLoS ONE. https://doi.org/10.1371/journal.pone.0240968Responsibility, normalisation and negotiations of harm: E-cigarette users' opinions and experiences of vaping around children
Ward, E., Dawkins, L., Holland, R. and Notley, C. (2020). Responsibility, normalisation and negotiations of harm: E-cigarette users' opinions and experiences of vaping around children. International Journal of Drug Policy. 88, p. 103016. https://doi.org/10.1016/j.drugpo.2020.103016Reported patterns of vaping to support long-term abstinence from smoking: a cross-sectional survey of a convenience sample of vapers
Gentry, S., Ward, E., Dawkins, L., Holland, R. and Notley, C. (2020). Reported patterns of vaping to support long-term abstinence from smoking: a cross-sectional survey of a convenience sample of vapers. Harm Reduction Journal. 17, p. 70. https://doi.org/10.1186/s12954-020-00418-8Data for: A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain
Dawkins, L., Cox, S., Tyler, A., Bauld, L, Ford, A, Robson, D, Hajek, P, Best, C, Li, J, Uny, I and Parrott, S (2020). Data for: A cluster feasibility trial to explore the uptake and use of e-cigarettes versus usual care offered to smokers attending homeless centres in Great Britain. London South Bank University. https://doi.org/10.18744/lsbu.8q255A qualitative exploration of consumers’ perceived impacts, behavioural reactions, and future reflections of the EU Tobacco Products Directive (2017) as applied to electronic cigarettes
Ward, E, Anholt, C, Gentry, S, Dawkins, L, Holland, R and Notely, C (2020). A qualitative exploration of consumers’ perceived impacts, behavioural reactions, and future reflections of the EU Tobacco Products Directive (2017) as applied to electronic cigarettes. Tobacco Use Insights. 13, pp. 1-9. https://doi.org/10.1177/1179173X20925458Daily exposure to formaldehyde and acetaldehyde and potential health risk associated with use of high and low nicotine e-liquid concentrations
Kosmider, L, Cox, S, Marzena, Z, Jolanta, K, Goniewicz, M, McRobbie, H, Kimber, C and Dawkins, L (2020). Daily exposure to formaldehyde and acetaldehyde and potential health risk associated with use of high and low nicotine e-liquid concentrations. Scientific Reports. 10 (6546). https://doi.org/10.1038/s41598-020-63292-1Smoking amongst adults experiencing homelessness: A systematic review of prevalence rates, interventions and the barriers and facilitators to quitting and staying quit
Soar, K., Dawkins, L., Robson, D. and Cox, S. (2020). Smoking amongst adults experiencing homelessness: A systematic review of prevalence rates, interventions and the barriers and facilitators to quitting and staying quit. Journal of Smoking Cessation. 15 (2), pp. 94-108. https://doi.org/10.1017/jsc.2020.11Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions.
Kimber, C., Frings, D., Cox, S., Albery, I. and Dawkins, L. (2020). Communicating the Relative Health Risks of E-Cigarettes: An online experimental study exploring the Effects of a Comparative Health Message versus the EU Nicotine Addiction Warnings on Smokers’ and Non-Smokers’ Risk Perceptions and Behavioural Intentions. Addictive Behaviors. 101, p. 106177. https://doi.org/10.1016/j.addbeh.2019.106177E-cigarettes compared with nicotine replacement therapy within the UK stop smoking services: The TEC RCT
Hajek, P, Phillips-Waller, A, Przulj, D, Pesola, F, Smith, KM, Bisal, N, Li, J, Parrott, S, Sasieni, P, Dawkins, L, Ross, L, Goniewicz, M, Wu, Q and McRobbie, HJ (2019). E-cigarettes compared with nicotine replacement therapy within the UK stop smoking services: The TEC RCT. Health Technology Assessment. 23 (43), pp. vii-81. https://doi.org/10.3310/hta23430A systematic review of smoking, smoking cessation and the homeless: there is a will but is there a way?
Cox, S., Dawkins, L., Robson, D. and Soar, K. (2019). A systematic review of smoking, smoking cessation and the homeless: there is a will but is there a way? Lisbon Addictions Conference 2019. Lisbon 09 - 11 Oct 2019Investigating within-person patterns and trajectories of dual e-cigarette and tobacco use: the TRAJECT mixed methods study protocol
Cox, S., Notley, C., Dawkins, L., Naughton, F., Beard, E., Kimber, C., Ward, E., Holland, R. and Kwasnicka, D. (2019). Investigating within-person patterns and trajectories of dual e-cigarette and tobacco use: the TRAJECT mixed methods study protocol. Society for Research on Nicotine and Tobacco. Oslo 17 - 21 Sep 2019Cost-effectiveness of e-cigarettes compared with nicotine replacement therapy in stop smoking services in England (TEC study): a randomised controlled trial
Li, J., Hajek, P., Pesola, F., Wu, Q., Phillips-Waller, A., Przuli, D., Myers Smith, K., Bisal, N., Sasieni, P., Dawkins, L., Ross, L., Goniewicz, M., McRobbie, H. and Parrott, S. (2019). Cost-effectiveness of e-cigarettes compared with nicotine replacement therapy in stop smoking services in England (TEC study): a randomised controlled trial. Addiction. 115 (3), pp. 507-517. https://doi.org/10.1111/add.14829