PICaSSO Histologic Remission Index (PHRI) in Ulcerative Colitis – Development of a Novel Simplified Histological Score for Monitoring Mucosal Healing and Predicting Clinical Outcomes and its Applicability in an Artificial Intelligence System
Journal article
Gui, X., Bazarova, A., del Amor, R., Vieth, M., de Hertogh, G., Villanacci, V., Zardo, D., Parigi, T. L., Røyset, E., Shivaji, U., Monica, M. A.T., Mandelli, G., Bhandari, P., Danese, S., Ferraz, J., Hayee, B., Lazarev, M., Parra-Blanco, A., Pastorelli, L., Panaccione, R., Rath, T., Tontini, G.E., Ralf, H., Bisschops, R., Grisan, E., Naranjo, V., Ghosh, S. and Iacucci, M. (2022). PICaSSO Histologic Remission Index (PHRI) in Ulcerative Colitis – Development of a Novel Simplified Histological Score for Monitoring Mucosal Healing and Predicting Clinical Outcomes and its Applicability in an Artificial Intelligence System. Gut. https://doi.org/10.1136/gutjnl-2021-326376
Authors | Gui, X., Bazarova, A., del Amor, R., Vieth, M., de Hertogh, G., Villanacci, V., Zardo, D., Parigi, T. L., Røyset, E., Shivaji, U., Monica, M. A.T., Mandelli, G., Bhandari, P., Danese, S., Ferraz, J., Hayee, B., Lazarev, M., Parra-Blanco, A., Pastorelli, L., Panaccione, R., Rath, T., Tontini, G.E., Ralf, H., Bisschops, R., Grisan, E., Naranjo, V., Ghosh, S. and Iacucci, M. |
---|---|
Abstract | Histological assessment is critical for the management of ulcerative colitis (UC). We aimed to develop a simple histologic index, aligned to endoscopy, correlated with clinical outcomes, and easy to apply to a computer aided diagnosis (CAD) system to evaluate inflammatory activity. |
Keywords | Inflammatory bowel disease (IBD); ulcerative colitis (UC); endoscopic remission (ER); mucosal healing (MH); histologic remission (HR); histologic healing (HH); histological index; artificial intelligence (AI); machine learning; computer aided diagnosis |
Year | 2022 |
Journal | Gut |
Publisher | BMJ |
Digital Object Identifier (DOI) | https://doi.org/10.1136/gutjnl-2021-326376 |
Web address (URL) | http://dx.doi.org/10.1136/gutjnl-2021-326376 |
Publication dates | |
Online | 16 Feb 2022 |
Publication process dates | |
Accepted | 22 Jan 2022 |
Deposited | 28 Jan 2022 |
Publisher's version | License File Access Level Open |
Accepted author manuscript | License File description Accepted manuscript File Access Level Controlled |
https://openresearch.lsbu.ac.uk/item/8z188
Download files
196
total views59
total downloads0
views this month0
downloads this month