Prevalence and experience of fatigue in survivors of critical illness: a mixed‐methods systematic review

Journal article


Bench, S., Stayt, L., Shah, A., Dhiman, P. and Czuber‐Dochan, W. (2021). Prevalence and experience of fatigue in survivors of critical illness: a mixed‐methods systematic review. Anaesthesia. 76 (9), pp. 1233-1244. https://doi.org/10.1111/anae.15441
AuthorsBench, S., Stayt, L., Shah, A., Dhiman, P. and Czuber‐Dochan, W.
Abstract

We conducted a mixed methods systematic review to investigate the prevalence, experience and management of fatigue in survivors of critical illness. We identified 76 studies investigating fatigue or vitality in adults discharged from an ICU and extracted data were split into three datasets: vitality scores from the Short Form Health Survey SF-36 (n=54); other quantitative data (n=19); and qualitative data (n=9). We assessed methodological quality using critical appraisal skills programme tools. We adopted a segregated approach to mixed-methods synthesis. In a final step, we attributed combined results to one of four qualitative themes: prevalence and severity; contributing factors; impacts on quality of life; assessment and management. Prevalence of fatigue ranged from 13.8 to 80.9%. SF-36 vitality scores were commonly used as a marker of fatigue. Vitality scores reached a nadir approximately one-month post-ICU discharge (Mean (SD) 56.44 (32.30); 95%CI 52.92 - 59.97), improved over time but seldom reached reference population scores. Associated biological, disease-related and psychological factors included age, poor pre-morbid status, sleep and psychological disturbance. Qualitative data highlight the profound negative impact of fatigue on survivors’ quality of life. Survivors seldom had any information provided on the potential impact of fatigue. No fatigue assessment tools specific for critical illness or evidence-based interventions were reported. Fatigue is highly prevalent in survivors of critical illness and negatively impacts recovery. Further research on developing fatigue assessment tools specifically for critically ill patients and evaluating the impact of pharmacological and non-pharmacology interventions is needed.

KeywordsAnesthesiology and Pain Medicine
Year2021
JournalAnaesthesia
Journal citation76 (9), pp. 1233-1244
PublisherWiley
ISSN0003-2409
1365-2044
Digital Object Identifier (DOI)https://doi.org/10.1111/anae.15441
Publication dates
Print11 Mar 2021
Online11 Mar 2021
Publication process dates
Accepted13 Oct 2020
Deposited24 Oct 2020
Accepted author manuscript
File Access Level
Open
Additional information

This is the peer reviewed version of the following article: Bench, S (2020) Prevalence and experience of fatigue in survivors of critical illness: A mixed-methods systematic review, Anaesthesia. Which will be published in final form at https://associationofanaesthetists-publications.onlinelibrary.wiley.... This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

Licensehttp://onlinelibrary.wiley.com/termsAndConditions#vor
Permalink -

https://openresearch.lsbu.ac.uk/item/8qz40

Download files


Accepted author manuscript
  • 117
    total views
  • 61
    total downloads
  • 1
    views this month
  • 3
    downloads this month

Export as

Related outputs

Fatigue After CriTical illness (FACT): Co-production of a self-management intervention to support people with fatigue after critical illness
Brown, S.E., Shah, A., Czuber-Dochan, W., Bench, S. and Stayt, L. (2024). Fatigue After CriTical illness (FACT): Co-production of a self-management intervention to support people with fatigue after critical illness. Intensive and Critical Care Nursing. 82, p. 103659. https://doi.org/10.1016/j.iccn.2024.103659
Experiences of siblings of children with congenital heart disease during Coronavirus disease 2019; A qualitative interview study.
Bichard, E., McKeever, S., Bench, S. and Wray, J. (2022). Experiences of siblings of children with congenital heart disease during Coronavirus disease 2019; A qualitative interview study. Journal of Pediatric Nursing. https://doi.org/10.1016/j.pedn.2021.12.019
How COVID-19 has affected staffing models in intensive care: A qualitative study examining alternative staffing models (SEISMIC).
Endacott, R., Pearce, S., Rae, P., Richardson, A., Bench, S., Pattison, N. and SEISMIC Study Team (2021). How COVID-19 has affected staffing models in intensive care: A qualitative study examining alternative staffing models (SEISMIC). Journal of Advanced Nursing. https://doi.org/10.1111/jan.15081
Clinical Academic Research Internships: what works for nurses and the wider nursing, midwifery and allied health professional workforce
Olive, P., Maxton, Fiona, Bell, Cate Ann, Bench, Suzanne, Tinkler, Linda, Jones, Steph and Kenkre, Joyce (2020). Clinical Academic Research Internships: what works for nurses and the wider nursing, midwifery and allied health professional workforce. Journal of Clinical Nursing. https://doi.org/10.1111/jocn.15611
Exploring adult critical illness survivors’ experiences of fatigue; a qualitative study
Bench, S., Czuber-Dochan, W., Shah, A. and Stayt, L. (2021). Exploring adult critical illness survivors’ experiences of fatigue; a qualitative study. Journal of Advanced Nursing. https://doi.org/10.1111/jan.14995
Healthcare stakeholders’ perceptions and experiences of factors affecting the implementation of critical care telemedicine (CCT): qualitative evidence synthesis
Xyrichis, A., Iliopoulou, K., Mackintosh, N.J., Bench, S., Terblanche, M., Philippou, J. and Sandall, J. (2021). Healthcare stakeholders’ perceptions and experiences of factors affecting the implementation of critical care telemedicine (CCT): qualitative evidence synthesis. Cochrane Database of Systematic Reviews. 2017 (11). https://doi.org/10.1002/14651858.cd012876.pub2
Critical Care Nurses' Views and Experiences of Preanalytical Factors Influencing Point-of-Care Testing A Qualitative Study
Bench, S. (2020). Critical Care Nurses' Views and Experiences of Preanalytical Factors Influencing Point-of-Care Testing A Qualitative Study. Point of Care: The Journal of Near-Patient Testing and Technology. 19 (4), pp. 97-100. https://doi.org/10.1097/POC.0000000000000212
Empathy in Action in Healthcare (EACH): A mixed methods study of nurses' and therapists’ empathy
Catlow, R, Aikins-Snyper, F, Carson, M, Jaggi, A and Bench, S (2020). Empathy in Action in Healthcare (EACH): A mixed methods study of nurses' and therapists’ empathy. International Journal of Orthopaedic and Trauma Nursing. https://doi.org/10.1016/j.ijotn.2020.100777
Patient and Family Member Experiences in Critical Care Research and Quality Improvement Projects
Bench, S, O'Shea, A and Boaz, Z (2020). Patient and Family Member Experiences in Critical Care Research and Quality Improvement Projects. Nursing Research. https://doi.org/10.1097/nnr.0000000000000443
Neurological Alterations and Management
Bench, S. (2019). Neurological Alterations and Management. in: Aitken, L., Marshall, A. and Chaboyer, W. (ed.) Critical Care Nursing Elsevier.
Involving patients and families in critical care research and quality improvement
Bench, S (2019). Involving patients and families in critical care research and quality improvement. Nursing in Critical Care. 24 (2), pp. 67-69. https://doi.org/10.1111/nicc.12418
Randomised Controlled Trials: an introduction for nurse researchers
Bench, S, Day, T and Metcalfe, A (2013). Randomised Controlled Trials: an introduction for nurse researchers. Nurse Researcher. 20 (5), pp. 38-44. https://doi.org/10.7748/nr2013.05.20.5.38.e312
Evaluating the implementation of confusion assessment method-intensive care unit using a quality improvement approach
Stewart, C. and Bench, S. (2018). Evaluating the implementation of confusion assessment method-intensive care unit using a quality improvement approach. Nursing in Critical Care. 23 (4), pp. 172-178. https://doi.org/10.1111/nicc.12354
Ventilator-associated pneumonia and suction: a review of the literature
Letchford, E and Bench, S (2018). Ventilator-associated pneumonia and suction: a review of the literature. British Journal of Nursing. 27 (1), pp. 13-18. https://doi.org/10.12968/bjon.2018.27.1.13
The education and training needs of advanced clinical practitioners: an exploratory, qualitative study
Bench, S, Lee, G, Baker, E, Trenchard-Turner, N, Whaley, S, Peacock, S, Garry, B, Dover, N, Nwosu, W and Worth, T (2018). The education and training needs of advanced clinical practitioners: an exploratory, qualitative study. Journal of Nursing Education and Practice. 8 (8). https://doi.org/10.5430/jnep.v8n8p66
Reviewing interventions supporting parents' well-being after a child’s intensive care unit discharge
Bench, S and Bedford, Z (2018). Reviewing interventions supporting parents' well-being after a child’s intensive care unit discharge. Nursing in Critical Care. https://doi.org/10.1111/nicc.12405
The nature and extent of service user involvement in critical care research and quality improvement; a scoping review of the literature.
Bench, S, Eassom, E and Poursanidou, K (2017). The nature and extent of service user involvement in critical care research and quality improvement; a scoping review of the literature. International Journal of Consumer Studies. 42 (2), pp. 217-231. https://doi.org/10.1111/ijcs.12406
Intensive care discharge summaries for general practice staff: a focus group study
Bench, S, Cornish, J and Xyrichis, A (2016). Intensive care discharge summaries for general practice staff: a focus group study. British Journal of General Practice. 66 (653), pp. e904-e912. https://doi.org/10.3399/bjgp16X688045
Evaluating the feasibility and effectiveness of a critical care discharge information pack for patients and their families: a pilot cluster randomised controlled trial
Bench, S, Day, T, Heelas, K, Hopkins, P, White, C and Griffiths, P (2015). Evaluating the feasibility and effectiveness of a critical care discharge information pack for patients and their families: a pilot cluster randomised controlled trial. BMJ Open. 5 (11), pp. e006852-e006852. https://doi.org/10.1136/bmjopen-2014-006852
Providing critical care patients with a personalised discharge summary: A questionnaire survey and retrospective analysis exploring feasibility and effectiveness
Bench, S, Heelas, K, White, C and Griffiths, P (2014). Providing critical care patients with a personalised discharge summary: A questionnaire survey and retrospective analysis exploring feasibility and effectiveness. Intensive and Critical Care Nursing. 30 (2), pp. 69-76. https://doi.org/10.1016/j.iccn.2013.08.007
Effectiveness of Critical Care Discharge Information in Supporting Early Recovery From Critical Illness
Bench, S, Day, T and Griffiths, P (2013). Effectiveness of Critical Care Discharge Information in Supporting Early Recovery From Critical Illness. Critical Care Nurse. 33 (3), pp. 41-52. https://doi.org/10.4037/ccn2013134
Developing user centred critical care discharge information to support early critical illness rehabilitation using the Medical Research Council's complex interventions framework
Bench, S, Day, TL and Griffiths, P (2012). Developing user centred critical care discharge information to support early critical illness rehabilitation using the Medical Research Council's complex interventions framework. Intensive and Critical Care Nursing. 28 (2), pp. 123-131. https://doi.org/10.1016/j.iccn.2012.02.002
Involving Users in the Development of Effective Critical Care Discharge Information: A Focus Group Study
Bench, S, Day, T and Griffiths, P (2011). Involving Users in the Development of Effective Critical Care Discharge Information: A Focus Group Study. American Journal of Critical Care. 20 (6), pp. 443-452. https://doi.org/10.4037/ajcc2011829
The user experience of critical care discharge: A meta-synthesis of qualitative research
Bench, S and Day, T (2010). The user experience of critical care discharge: A meta-synthesis of qualitative research. International Journal of Nursing Studies. 47 (4), pp. 487-499. https://doi.org/10.1016/j.ijnurstu.2009.11.013
Recognition and management of critical illness by midwives: implications for service provision
Bench, S (2007). Recognition and management of critical illness by midwives: implications for service provision. Journal of Nursing Management. 15 (3), pp. 348-356. https://doi.org/10.1111/j.1365-2834.2007.00759.x
Clinical skills: assessing and treating shock: a nursing perspective
Bench, S (2004). Clinical skills: assessing and treating shock: a nursing perspective. British Journal of Nursing. 13 (12), pp. 715-721. https://doi.org/10.12968/bjon.2004.13.12.13260