The effects of femoral metaphyseal morphology on growth plate biomechanics in juvenile chimpanzees and humans

Journal article


Stamos, P. and Berthaume, M.A. (2021). The effects of femoral metaphyseal morphology on growth plate biomechanics in juvenile chimpanzees and humans. Interface Focus. 11 (5), p. 20200092. https://doi.org/10.1098/rsfs.2020.0092
AuthorsStamos, P. and Berthaume, M.A.
AbstractThe distal femoral metaphyseal surface presents dramatically different morphologies in juvenile extant hominoids—humans have relatively flat metaphyseal surfaces when compared with the more complex metaphyseal surfaces of apes. It has long been speculated that these different morphologies reflect different biomechanical demands placed on the growth plate during locomotor behaviour, with the more complex metaphyseal surfaces of apes acting to protect the growth plate during flexed-knee behaviours like squatting and climbing. To test this hypothesis, we built subject-specific parametric finite-element models from the surface scans of the femora of five Pan and six Homo juveniles. We then simulated the loading conditions of either a straight-leg or flexed-knee gait and measured the resulting stresses at the growth plate. When subjected to the simulated flexed-knee loading conditions, both the maximum and mean von Mises stresses were significantly lower in the Pan models than in the Homo models. Further, during these loading conditions, von Mises stresses were strongly negatively correlated with ariaDNE, a measure of complexity of the metaphyseal surface. These results indicate that metaphyseal surface morphology has a robust effect on growth plate mechanics.
KeywordsBiotechnology; Biophysics; Biochemistry; Bioengineering; Biomaterials; Biomedical Engineering
Year2021
JournalInterface Focus
Journal citation11 (5), p. 20200092
PublisherThe Royal Society
ISSN2042-8901
Digital Object Identifier (DOI)https://doi.org/10.1098/rsfs.2020.0092
Funder/ClientWenner-Gren Foundation
University of California, Davis, Department of Anthropology
Publication dates
Online13 Aug 2021
Print06 Oct 2021
Publication process dates
Accepted15 Jun 2021
Deposited06 Oct 2021
Accepted author manuscript
License
File Access Level
Open
Permalink -

https://openresearch.lsbu.ac.uk/item/8xq78

Download files


Accepted author manuscript
RFFS_Proof_Revision2.pdf
License: CC BY 4.0
File access level: Open

  • 3
    total views
  • 10
    total downloads
  • 3
    views this month
  • 2
    downloads this month

Export as

Related outputs

Introduction to the theme issue ‘Biological anthroengineering’
Kramer, P. and Berthaume, M. (2021). Introduction to the theme issue ‘Biological anthroengineering’. Interface Focus. 11 (5), p. 20210058. https://doi.org/10.1098/rsfs.2021.0058
Anthroengineering: an independent interdisciplinary field
Berthaume, M. and Kramer, P. (2021). Anthroengineering: an independent interdisciplinary field. Interface Focus. 11 (5), p. 20200056. https://doi.org/10.1098/rsfs.2020.0056
Molar biomechanical function in South African hominins Australopithecus africanus and Paranthropus robustus
Berthaume, M. and Kupczik, K. (2021). Molar biomechanical function in South African hominins Australopithecus africanus and Paranthropus robustus. Interface Focus. 11 (5), p. 20200085. https://doi.org/10.1098/rsfs.2020.0085
Cyamella (a popliteal sesamoid bone) prevalence: A systematic review, meta‐analysis, and proposed classification system
Berthaume, M. and Bull, A. (2021). Cyamella (a popliteal sesamoid bone) prevalence: A systematic review, meta‐analysis, and proposed classification system. Clinical anatomy. pp. 1-11. https://doi.org/10.1002/ca.23743
The landscape of tooth shape: Over 20 years of dental topography in primates
Berthaume, M., Lazzari, Vincent and Guy, Franck (2020). The landscape of tooth shape: Over 20 years of dental topography in primates. Evolutionary anthropology. 29 (5), pp. 245-262. https://doi.org/10.1002/evan.21856
Unique myological changes associated with ossified fabellae: a femorofabellar ligament and systematic review of the double-headed popliteus
Berthaume, M. A., Barnes, S., Athwal, K.K. and Willinger, L. (2020). Unique myological changes associated with ossified fabellae: a femorofabellar ligament and systematic review of the double-headed popliteus. PeerJ. 8, pp. e10028-e10028. https://doi.org/10.7717/peerj.10028
Fabella prevalence rate increases over 150 years, and rates of other sesamoid bones remain constant: a systematic review
Berthaume, M., Di Federico, E. and Bill, A. (2019). Fabella prevalence rate increases over 150 years, and rates of other sesamoid bones remain constant: a systematic review. Journal of Anatomy. 235, pp. 67-79. https://doi.org/10.1111/joa.12994
Effects of cropping, smoothing, triangle count, and mesh resolution on 6 dental topographic metrics
Berthaume, M., Winchester, J. and Kupczik, K (2019). Effects of cropping, smoothing, triangle count, and mesh resolution on 6 dental topographic metrics. PLoS ONE. 14 (5), p. e0216229. https://doi.org/10.1371/journal.pone.0216229
Ambient occlusion and PCV (portion de ciel visible): A new dental topographic metric and proxy of morphological wear resistance
Berthaume, M., Winchester, J. and Kupczik, K. (2019). Ambient occlusion and PCV (portion de ciel visible): A new dental topographic metric and proxy of morphological wear resistance. PLoS ONE. 14 (5), p. e0215436. https://doi.org/10.1371/journal.pone.0215436
Human biological variation in sesamoid bone prevalence: the curious case of the fabella
Berthaume, M. and Bull, A.M.J. (2019). Human biological variation in sesamoid bone prevalence: the curious case of the fabella. Journal of Anatomy. https://doi.org/10.1111/joa.13091
Dental topography and the diet of Homo naledi
Berthaume, M., Delezene, L. and Kupczik, K. (2018). Dental topography and the diet of Homo naledi. Journal of Human Evolution. 118, pp. 14-26. https://doi.org/10.1016/j.jhevol.2018.02.006
Extant ape dental topography and its implications for reconstructing the emergence of early Homo
Berthaume, M. and Schroer, K. (2017). Extant ape dental topography and its implications for reconstructing the emergence of early Homo. Journal of Human Evolution. 112, pp. 15-29. https://doi.org/10.1016/j.jhevol.2017.09.001
Functional and evolutionary consequences of cranial fenestration in birds
Gussekloo, S., Berthaume, M., Pulaski, D., Westbroek, I., Waarsing, J., Heinen, R., Grosse, I. and Dumont, E. (2017). Functional and evolutionary consequences of cranial fenestration in birds. Evolution. 71 (5), pp. 1327-1338. https://doi.org/10.1111/evo.13210
Skeletal Immaturity, Rostral Sparing, and Disparate Hip Morphologies as Biomechanical Causes for Legg-Calve-Perthes’ Disease
Berthaume, M., Perry, D.C., Dobson, C., Witzel, U., Clarke, N.M. and Fagan, M. (2016). Skeletal Immaturity, Rostral Sparing, and Disparate Hip Morphologies as Biomechanical Causes for Legg-Calve-Perthes’ Disease . Clinical Anatomy. https://doi.org/10.1002/ca.22690
On the relationship between tooth shape and masticatory efficiency: a finite element study
Berthaume, M. (2016). On the relationship between tooth shape and masticatory efficiency: a finite element study. The Anatomical Record. 299 (5), pp. 679-687. https://doi.org/10.1002/ar.23328
Food mechanical properties and dietary ecology
Berthaume, M. (2016). Food mechanical properties and dietary ecology. Americal Journal of Physical Anthropology. 159, pp. 79-104. https://doi.org/10.1002/ajpa.22903
What did Hadropithecus eat, and why should paleoanthropologists care?
Godfrey, L., Crowley, B., Muldoon, K., Kelley, E., King, S., Best, A. and Berthaume, M. (2016). What did Hadropithecus eat, and why should paleoanthropologists care? American Journal of Primatology. 78 (10), pp. 1098-1112. https://doi.org/10.1002/ajp.22506
Mechanical evidence that Australopithecus sediba was limited in its ability to eat hard foods
Ledogar, J., Smith, A., Benazzi, S., Weber, G., Spencer, M., Carlson, K., McNulty, K., Dechow, P., Grosse, I., Ross, C., Richmond, B., Wright, B., Wang, Q., Byron, C., Carlson, K., de Ruiter, D., Berger, L., Tamvada, K., Pryor, L., Berthaume, M. and Strait, D. (2016). Mechanical evidence that Australopithecus sediba was limited in its ability to eat hard foods. Nature Communications. 7 (1). https://doi.org/10.1038/ncomms10596
The Feeding Biomechanics and Dietary Ecology of Paranthropus boisei
Smith, A., Benazzi, S, Ledogar, J., Tamvada, K., Pryor Smith, L., Weber, G., Spencer, M., Lucas, P., Michael, S., Shekeban, A., Al-Fadhalah, K., Almusallam, A, Dechow, P., Grosse, I., Ross, C., Madden, R., Richmond, B., Wright, B., Wang, Q, Byron, C., Slice, D., Wood, S., Dzialo, C., Berthaume, M., van Casteren, A. and Strait, D. (2015). The Feeding Biomechanics and Dietary Ecology of Paranthropus boisei. The Anatomical Record. 298 (1), pp. 145-167. https://doi.org/10.1002/ar.23073
The effects of relative food item size on optimal tooth cusp sharpness during brittle food item processing
Berthaume, M., Dumont, E., Godfrey, L. and Grosse, I. (2014). The effects of relative food item size on optimal tooth cusp sharpness during brittle food item processing. Interface. 11 (101), p. 20140965. https://doi.org/10.1098/rsif.2014.0965