The path from schizotypy to depression and aggression and the role of family stress

Journal article

Premkumar, P., Kuipers, E. and Kumiar, V. (2020). The path from schizotypy to depression and aggression and the role of family stress. European Psychiatry. 63 (1), p. e79. https://doi.org/10.1192/j.eurpsy.2020.76
AuthorsPremkumar, P., Kuipers, E. and Kumiar, V.
Abstract

Background.
Schizotypy is a multidimensional construct that is linked to the vulnerability for psychosis. Positive schizotypy includes having paranormal beliefs. Negative schizotypy includes social anhedonia. Disorganized schizotypy includes social anxiety and communication disorder. Schizotypy relates to depression and aggression. Family stress from high expressed emotion (EE; a rating of criticism, hostility, and emotional overinvolvement in a close relative toward a person showing signs of mental disorder) may mediate the link between schizotypy, depression and aggression. This study tested, using path analyses, the hypotheses that schizotypy predicts depression and aggression through high perceived EE as criticism and irritability (hypothesis 1) and praise and intrusiveness in a close relative (hypothesis 2).
Methods.
One hundred and four healthy participants listened to and rated the self-relevance of standard criticism and standard praise that denote EE. Participants rated their level of schizotypy, depression, aggression, and perceived EE in self-report questionnaires. Two path models tested the hypotheses.
Results.
Disorganized schizotypy, more than positive schizotypy, predicted the path to depression and aggression when perceived criticism and perceived EE-irritability were mediators. Disorganised schizotypy, more than negative schizotypy, predicted the path to depression and aggression when perceived praise and perceived EE-intrusiveness were mediators.
Conclusions.
Greater perceived criticism and less perceived praise in family communication explain the path from disorganized schizotypy (more so than positive or negative schizotypy) to depression and aggression. These findings indicate a need to consider the thought disorder-EE link as a potential contributor to depression and aggression in people with schizophrenia.

KeywordsArousal; criticism; disorganization; expressed emotion; path analysis; praise
Year2020
JournalEuropean Psychiatry
Journal citation63 (1), p. e79
Digital Object Identifier (DOI)https://doi.org/10.1192/j.eurpsy.2020.76
Web address (URL)https://www.cambridge.org/core/journals/european-psychiatry/article/path-from-schizotypy-to-depression-and-aggression-and-the-role-of-family-stress/D9A18E414CEEDE7B542C2990F22D72DD
Publication dates
Print30 Jul 2020
Publication process dates
Accepted22 Jul 2020
Deposited13 Oct 2020
Publisher's version
License
File Access Level
Open
Accepted author manuscript
License
File Access Level
Controlled
Permalink -

https://openresearch.lsbu.ac.uk/item/8qv74

Download files

Publisher's version
path_from_schizotypy_to_depression_and_aggression_and_the_role_of_family_stress.pdf
License: CC BY 4.0
File access level: Open

  • 89
    total views
  • 43
    total downloads
  • 0
    views this month
  • 0
    downloads this month

Export as

Related outputs

Multiscale Fluctuation Dispersion Entropy of EEG as a Physiological Biomarker of Schizotypy
Zandbagleh, A., Azami, H., Mirzakuchaki, S., Daliri, M. R., Sanei, S. and Premkumar, P. (2023). Multiscale Fluctuation Dispersion Entropy of EEG as a Physiological Biomarker of Schizotypy. IEEE Access. pp. 110124 - 110135. https://doi.org/10.1109/ACCESS.2023.3321868
The relationships between expressed emotion, cortisol, and EEG alpha asymmetry
Wang, G.Y., Crook-Rumsey, M., Sumich, A., Dulson, D., Gao,T. T. and Premkumar, P. (2023). The relationships between expressed emotion, cortisol, and EEG alpha asymmetry. Physiology and Behavior. 269 (114276). https://doi.org/10.1016/j.physbeh.2023.114276
Enhancing biofeedback-driven self-guided virtual reality exposure therapy through arousal detection from multimodal data using machine learning
Rahman, M.A., Brown, D.J., Mahmud, M., Harris, M., Shopland, N., Heym, N., Sumich, A., Turabee, Z. B., Standen, B., Downes, D., Xing,Y., Thomas, C., Haddick, S., Premkumar, P., Nastase, S., Burton, A. and Lewis, J. (2023). Enhancing biofeedback-driven self-guided virtual reality exposure therapy through arousal detection from multimodal data using machine learning. Brain Informatics. 10 (14). https://doi.org/10.1186/s40708-023-00193-9
Reflecting on the experiential journey: Creating, developing and understanding leadership in Equality, Diversity and Inclusion within a Faculty
Premkumar, P., Leadley-Meade, Z., Moorley, C., Rye, S., Clegg, D. and Alasia, S. (2023). Reflecting on the experiential journey: Creating, developing and understanding leadership in Equality, Diversity and Inclusion within a Faculty. Equality, Diversity and Inclusion Conference 2023: The Shoulders of Giants: Listening, Learning and Improving our Practice.
Tensor factorization approach for ERP-based assessment of schizotypy in a novel auditory oddball task on perceived family stress
Zandbagleh, A, Mirzakuchaki, S., Daliri, M.R., Premkumar, P., Carretié, L. and Saeid Sanei, S. (2022). Tensor factorization approach for ERP-based assessment of schizotypy in a novel auditory oddball task on perceived family stress. Journal of Neural Engineering. https://doi.org/10.1088/1741-2552/aca69f
Conceptualising mental illness among University students of African, Caribbean and similar ethnic heritage in the United Kingdom
Dare, T., Jidong, D. E. and Premkumar, P. (2022). Conceptualising mental illness among University students of African, Caribbean and similar ethnic heritage in the United Kingdom. Ethnicity & health. 28 (7), pp. 522-543. https://doi.org/10.1080/13557858.2022.2104817
What is next for the neurobiology of temperament, personality and psychopathology?
Trofimova, I., Bajaj, S., Bashkatov, S. A., Blair, J., Brandt, A., , Chan, R. C. K., Clemens, B., Corr, P. J., Cyniak-Cieciura, M., Demidova, L., Filippi, C. A., Garipova, M., Habel, U., Haines, U., Heym, N., Hunter, K., Jones, N. A., Kanen, J., Kirenskaya, A., Kumari, V., Lenzoni, S., Lui, S. S. Y., Mathur,A., McNaughton, N., Mize, K. D., Mueller, E., Netter, P., Paul, K., Plieger, T., Premkumar, P., Raine, A., Reuter, M., Robbins, T. W., Samylkin, D., Storozheva, Z., Sulis, W., Sumich, A., Tkachenko, A., Valadez, E. A., Wacker, J., Wagels, L., Wang, L.-L., Zawadzki, B. and Pickering, A. D. (2022). What is next for the neurobiology of temperament, personality and psychopathology? Current Opinion in Behavioral Sciences. 45 (101143). https://doi.org/10.1016/j.cobeha.2022.101143
Classification of Low and High Schizotypy Levels via Evaluation of Brain Connectivity
Zandbagleh, A., Mirzakuchaki, S, Daliri, M.R., Premkumar, P. and Sanei, S. (2022). Classification of Low and High Schizotypy Levels via Evaluation of Brain Connectivity. International Journal of Neural Systems. 34 (2). https://doi.org/10.1142/S0129065722500137
Rejection sensitivity and its relationship to schizotypy and aggression: current status and future directions
Premkumar, P. and Kumari, V. (2022). Rejection sensitivity and its relationship to schizotypy and aggression: current status and future directions. Current Opinion in Behavioral Sciences. 44. https://doi.org/10.1016/j.cobeha.2022.101110
Editorial: The Use of Virtual-Reality Interventions in Reducing Anxiety
Premkumar, P., Heym, N., Anderson, P. L., Brown, D. and Sumich A. (2022). Editorial: The Use of Virtual-Reality Interventions in Reducing Anxiety. Frontiers in Virtual Reality. 3 (853678). https://doi.org/10.3389/frvir.2022.853678
The Effectiveness of Self-Guided Virtual-Reality Exposure Therapy for Public-Speaking Anxiety
Premkumar, P., Heym, Nadja, Brown, David Joseph, Battersby, Steven, Sumich, Alexander, Huntington, Bethany, Daly, Rosie and Zysk, Eva (2021). The Effectiveness of Self-Guided Virtual-Reality Exposure Therapy for Public-Speaking Anxiety. Frontiers in Psychiatry. 12, p. 694610. https://doi.org/10.3389/fpsyt.2021.694610
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study
Modinos, G., Kirschner, M., Hodzic-Santor, B., Antoniades, M., Nenadic, I., Kircher, T., Krug, A., Meller, T., Grotegerd, D., Fornito, A., Arnatkeviciute, A., Bellgrove, M., Tiego, J., Dannlowski, U., Dohm, K., Hülsmann, C., Kugel, H., Enneking, V., Klug, M., Leehr, E., Boehnlein, J., Gruber, M., Mehler, D., DeRosse, P., Moyett, A., Baune, B., Green, M., Quidé, Y., Pantelis, C., Strachan, R., Wang, Y., Ettinger, U., Debbané, M., Derome, M., Gaser, C., Besteher, B., Diederen, K., Spencer, T., Fletcher, P., Rössler, W., Smigielski, L., Kumari, V., Premkumar, P., Park, H., Wiebels, K., Lemmers-Jansen, I., Gilleen, J., Allen, P., Kozhuharova, P., Marsman, J-B., Lebedeva, I., Tomyshev, A., Mukhorina, A., Kaiser, S., Fett, A.-K., Sommer, I., Schuite-Koops, S., Paquola, C., Lariviere, S., Bernhardt, B., Dagher, A., Grant, P., van Erp, T., Turner, J. A., Thompson, P. and Aleman, A. (2021). Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study. Molecular Psychiatry. https://doi.org/10.1038/s41380-021-01359-9
Pituitary volume in people with chronic schizophrenia: Clarifying the roles of serious violence and childhood maltreatment
Premkumar, P., Bipin, M., Das, M., Lau, J. Y. F., Sumich, A. L. and Kumari, V. (2021). Pituitary volume in people with chronic schizophrenia: Clarifying the roles of serious violence and childhood maltreatment. Psychiatry Research: Neuroimaging. 314, p. 111323. https://doi.org/10.1016/j.pscychresns.2021.111323
Mild-to-moderate schizotypal traits relate to physiological arousal from social stress
Premkumar, P., Alahakoon, P., Smith, M., Kumari, V., Babu, D. and Baker, J. (2020). Mild-to-moderate schizotypal traits relate to physiological arousal from social stress. Stress. https://doi.org/10.1080/10253890.2020.1797674
Neural responses to criticism and praise vary with schizotypy and perceived emotional support
Premkumar, P., Santo, M. G. E., Onwumere, O., Schürmann, M., Kumari, V., Blanco, S., Baker, J. and Kuipers, E. (2019). Neural responses to criticism and praise vary with schizotypy and perceived emotional support. International Journal of Psychophysiology. 145, pp. 109-118. https://doi.org/10.1016/j.ijpsycho.2019.05.008
Sensitivity to criticism and praise predicts schizotypy in the non-clinical population: The role of affect and perceived expressed emotion
Premkumar, P., Dunn, A. K., Onwumere, J. and Kuipers, E. (2019). Sensitivity to criticism and praise predicts schizotypy in the non-clinical population: The role of affect and perceived expressed emotion. European Psychiatry. 55, p. 109–115. https://doi.org/10.1016/j.eurpsy.2018.10.009
Deciphering reward-based decision making in schizophrenia: a meta-analysis and behavioral modelling of the Iowa Gambling Task
Premkumar, P., Betz, Linda T, Brambilla, Paolo, Ilankovic, Andrej, Premkumar, Preethi, Kim, Myung-Sun, Raffard, Stéphane, Bayard, Sophie, Hori, Hikaru, Lee, Kyoung-Uk, Lee, Seung Jae, Koutsouleris, Nikolaos and Kambeitz, Joseph (2019). Deciphering reward-based decision making in schizophrenia: a meta-analysis and behavioral modelling of the Iowa Gambling Task. Schizophrenia Research. 204, pp. 7-15. https://doi.org/10.1016/j.schres.2018.09.009
Developing and maintaining the teacher-student relationship in one to one alternative provision: the tutor’s experience
Premkumar, P., Fitzsimmons, W. and Trigg, R. (2019). Developing and maintaining the teacher-student relationship in one to one alternative provision: the tutor’s experience. Educational Review. https://doi.org/10.1080/00131911.2019.1653265
Pituitary volume reduction in schizophrenia following cognitive behavioural therapy
Premkumar, P., Bream, D., Sapara, A., Fannon, D., Anilkumar, A. P., Kuipers, E. and Kumari.V. (2018). Pituitary volume reduction in schizophrenia following cognitive behavioural therapy. Schizophrenia Research. 192, p. 416–422. https://doi.org/10.1016/j.schres.2017.04.035
Schizotypal traits and their relation to rejection sensitivity in the general population: Their mediation by quality of life, agreeableness and neuroticism
Premkumar, P., Onwumere, J., Betts, L., Kibowski, F. and Kuipers, E. (2018). Schizotypal traits and their relation to rejection sensitivity in the general population: Their mediation by quality of life, agreeableness and neuroticism. Psychiatry Research. 267, pp. 201-209. https://doi.org/10.1016/j.psychres.2018.06.002
Neural changes following cognitive behaviour therapy for psychosis: A longitudinal study
Kumari, V., Fannon, D., Peters, E.R., Ffytche, D.H., Sumich, A.L., Premkumar, P., Anilkumar, A.P., Andrew, C., Phillips, M.L., Williams, S.C.R. and Kuipers, E. (2011). Neural changes following cognitive behaviour therapy for psychosis: A longitudinal study. Brain. 134 (8), p. 2396–2407. https://doi.org/10.1093/brain/awr154