Is there an association between metabolic syndrome and rotator cuff related shoulder pain? A systematic review

Journal article

Burne, G., Mansfield, M., Gaida, J. and Lewis, J. (2019). Is there an association between metabolic syndrome and rotator cuff related shoulder pain? A systematic review. BMJ Open Sport and Exercise Medicine.
AuthorsBurne, G., Mansfield, M., Gaida, J. and Lewis, J.

Rotator cuff related shoulder pain (RCRSP) is a common upper limb complaint. It has been suggested that this condition is more common among people with cardiometabolic risk factors. This systematic review has synthesised evidence from case-control, cross-sectional and cohort studies on the association between metabolic syndrome (MetS) and RCRSP.

Design and Data Sources
Five medical databases (MEDLINE, EMBASE, SCOPUS, CINAHL and AMED) and reference checking methods were used to identify all relevant English articles that considered MetS and RCRSP.

Studies were appraised using the Newcastle Ottawa Scale (NOS). Two reviewers performed critical appraisal and data extraction. Narrative synthesis was performed via content analysis of statistically significant associations .

Three cross-sectional, two case-control and one cohort study met the inclusion criteria, providing a total of 1,187 individuals with RCRSP. Heterogeneity in methodology and RCRSP or MetS definition precluded a meaningful meta-analysis. Four of the included studies identified associations between the prevalence of MetS and RCRSP. Studies consistently identified independent cardiometabolic risk factors associated with RCRSP. All studies were level III evidence.

Summary and Conclusion
The low-moderate quality evidence included in this review suggests an association between MetS and RCRSP. Most studies demonstrated moderate quality on appraisal. The direction of association and cardiometabolic factors influencing should be investigated by longitudinal and treatment studies. These preliminary conclusions and clinical utility should be treated with caution due to limitations of the evidence base

JournalBMJ Open Sport and Exercise Medicine
PublisherBMJ Journals
Publication dates
Print06 Dec 2019
Publication process dates
Accepted03 Nov 2019
Deposited22 Nov 2019
Publisher's version
CC BY-NC 4.0
File Access Level
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Publisher's version
License: CC BY-NC 4.0
File access level: Open

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