Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: review of randomised controlled trials from 1997 to 2017

Journal article


Smith, T, Mansfield, M, Hawker, G, Hunter, D, March, L, Boers, M, Shea, B, Christensen, R, Guillemin, F, Terwee, C, Williamson, P, Roos, E, Loeser, R, Schnitzer, T, Kloppenburg, M, Neogi, T, Ladel, C, Kalsi, G, Kaiser, U, Buttel, T, Ashford, A, Mobasheri, A, Arden, N, Tennant, A, Hochberg, M, de Wit, M, Tugwell, P and Conaghan, P (2019). Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: review of randomised controlled trials from 1997 to 2017. Journal of Rheumatology.
AuthorsSmith, T, Mansfield, M, Hawker, G, Hunter, D, March, L, Boers, M, Shea, B, Christensen, R, Guillemin, F, Terwee, C, Williamson, P, Roos, E, Loeser, R, Schnitzer, T, Kloppenburg, M, Neogi, T, Ladel, C, Kalsi, G, Kaiser, U, Buttel, T, Ashford, A, Mobasheri, A, Arden, N, Tennant, A, Hochberg, M, de Wit, M, Tugwell, P and Conaghan, P
Abstract

Objective: To assess the uptake of the OMERACT-OARSI core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials. Methods: 382 trials of hip and/or knee OA were identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phase. Results: COS adoption decreased from 61% between 1997-2001 to 38% between 2012-2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient global assessment (48%) was the principal missing domain. Conclusion: Limited adoption of the COS Domains indicates that further consideration to improve implementation is required to improved uptake.

KeywordsOMERACT; Core Outcome Set; Domain; Adoption; Trial Registration; 1103 Clinical Sciences; 1107 Immunology; 1117 Public Health And Health Services; Arthritis & Rheumatology
Year2019
JournalJournal of Rheumatology
PublisherJournal of Rheumatology
ISSN1499-2752
Digital Object Identifier (DOI)doi:10.3899/jrheum.181066
Publication dates
Print01 Mar 2019
Publication process dates
Deposited16 Nov 2018
Accepted15 Nov 2018
Accepted author manuscript
License
CC BY 4.0
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https://openresearch.lsbu.ac.uk/item/86774

Accepted author manuscript

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