PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques
Journal article
Lillington, J., Brusaferri, L., Klaser, K., Shmueli, K., Neji, R., Hutton, B.F., Fraioli, F., Arridge, S., Cardoso, M.J., Ourselin, S., Thielemans, K. and Atkinson, D. (2019). PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques. Medical Physics. 47 (2), pp. 790-811. https://doi.org/10.1002/mp.13943
Authors | Lillington, J., Brusaferri, L., Klaser, K., Shmueli, K., Neji, R., Hutton, B.F., Fraioli, F., Arridge, S., Cardoso, M.J., Ourselin, S., Thielemans, K. and Atkinson, D. |
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Abstract | Positron emission tomography/magnetic resonance imaging (PET/MRI) potentially offers several advantages over positron emission tomography/computed tomography (PET/CT), for example, no CT radiation dose and soft tissue images from MR acquired at the same time as the PET. However, obtaining accurate linear attenuation correction (LAC) factors for the lung remains difficult in PET/MRI. LACs depend on electron density and in the lung, these vary significantly both within an individual and from person to person. Current commercial practice is to use a single-valued population-based lung LAC, and better estimation is needed to improve quantification. Given the under-appreciation of lung attenuation estimation as an issue, the inaccuracy of PET quantification due to the use of single-valued lung LACs, the unique challenges of lung estimation, and the emerging status of PET/MRI scanners in lung disease, a review is timely. This paper highlights past and present methods, categorizing them into segmentation, atlas/mapping, and emission-based schemes. Potential strategies for future developments are also presented. |
Year | 2019 |
Journal | Medical Physics |
Journal citation | 47 (2), pp. 790-811 |
Publisher | Wiley |
ISSN | 0094-2405 |
2473-4209 | |
Digital Object Identifier (DOI) | https://doi.org/10.1002/mp.13943 |
Web address (URL) | http://dx.doi.org/10.1002/mp.13943 |
Publication dates | |
Online | 03 Dec 2019 |
Publication process dates | |
Accepted | 20 Nov 2019 |
Deposited | 08 Feb 2024 |
Publisher's version | License File Access Level Open |
https://openresearch.lsbu.ac.uk/item/9654x
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Publisher's version
Medical Physics - 2019 - Lillington - PET MRI attenuation estimation in the lung A review of past present and potential.pdf | ||
License: CC BY 4.0 | ||
File access level: Open |
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