Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline

Journal article

Loeffen, EAH, Kremer, LCM, van de Wetering, MD, Mulder, RL, Font-Gonzalez, A, Dupuis, LL, Campbell, F, Tissing, WJE, Anghelescu, DL, Birnie, K, de Bont, J, Bredlau, AL, Cullen, P, Daniels, S, Dick, B, van Dijk, M, Dingeman, RS, Evan, E, Gegg, J, Gibson, F, van Grotel, M, Jibb, L, Kao, R, Knops, R, Kulkarni, K, Leroy, P, Liossi, C, Ljungman, G, McLean, J, Mensink, M, Michiels, E, Muckaden, MA, Newman, B, Positano, K, Rijsdijk, M, Rowe, E, Sangha, G, Stinson, J, Taddio, A, Taylor, H, Tutelman, P, Twycross, A, Wijnen, M and Zeltzer, L (2019). Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline. Pediatric Blood and Cancer. 66 (6), p. e27698. https://doi.org/10.1002/pbc.27698
AuthorsLoeffen, EAH, Kremer, LCM, van de Wetering, MD, Mulder, RL, Font-Gonzalez, A, Dupuis, LL, Campbell, F, Tissing, WJE, Anghelescu, DL, Birnie, K, de Bont, J, Bredlau, AL, Cullen, P, Daniels, S, Dick, B, van Dijk, M, Dingeman, RS, Evan, E, Gegg, J, Gibson, F, van Grotel, M, Jibb, L, Kao, R, Knops, R, Kulkarni, K, Leroy, P, Liossi, C, Ljungman, G, McLean, J, Mensink, M, Michiels, E, Muckaden, MA, Newman, B, Positano, K, Rijsdijk, M, Rowe, E, Sangha, G, Stinson, J, Taddio, A, Taylor, H, Tutelman, P, Twycross, A, Wijnen, M and Zeltzer, L
Abstract

© 2019 The Authors. Pediatric Blood & Cancer Published by Wiley Periodicals, Inc. Although pain is one of the most prevalent and bothersome symptoms children with cancer experience, evidence-based guidance regarding assessment and management is lacking. With 44 international, multidisciplinary healthcare professionals and nine patient representatives, we aimed to develop a clinical practice guideline (following GRADE methodology), addressing assessment and pharmacological, psychological, and physical management of tumor-, treatment-, and procedure-related pain in children with cancer. In this paper, we present our thorough methodology for this development, including the challenges we faced and how we approached these. This lays the foundation for our clinical practice guideline, for which there is a high clinical demand.

Year2019
JournalPediatric Blood and Cancer
Journal citation66 (6), p. e27698
ISSN1545-5009
Digital Object Identifier (DOI)https://doi.org/10.1002/pbc.27698
Publication dates
Print01 Jun 2019
Publication process dates
Deposited11 May 2019
Accepted24 Feb 2019
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Open
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