Identifying lifestyle factors associated to co-morbidity of obesity and psychiatric disorders, a pilot study

Journal article


Gaskell, C., Sarada, P., Aleem, E. and Bendriss, D.G. (2023). Identifying lifestyle factors associated to co-morbidity of obesity and psychiatric disorders, a pilot study. Frontiers in Public Health. 11, p. 1132994. https://doi.org/10.3389/fpubh.2023.1132994
AuthorsGaskell, C., Sarada, P., Aleem, E. and Bendriss, D.G.
AbstractObesity and psychiatric disorders are linked through a bidirectional association. Obesity rates have tripled globally in the past decades, and it is predicted that by 2025, one billion people will be affected by obesity, often with a co-morbidity such as depression. While this co-morbidity seems to be a global health issue, lifestyle factors associated to it differ between countries and are often attributed to more than one factor. Prior obesity studies were performed in Western populations; this is the first study that investigates lifestyle factors relating to obesity and mental health of the diverse population in Qatar, a country that has witnessed tremendous lifestyle change in a short time. In this pilot study, we surveyed 379 respondents to assess and compare the lifestyles of Qatar residents to the global population. However due to the high proportion of responses from the United Kingdom (UK) residents, we have made comparisons between Qatar residents and UK residents. We used chi-square analysis, spearman rank correlation and logistic regression to compare the lifestyle factors of individuals suffering from both increased BMI and mental health conditions. The types of food consumed, stress, exercise frequency and duration, alcohol and tobacco consumption, and sleep duration, were explored and results argue that different lifestyle factors can contribute to the same health condition, suggesting different mechanisms involved. We found that both groups reported similar sleep durations (p = 0.800), but that perception of sleep (p = 0.011), consumption of alcohol (p = 0.001), consumption of takeaway food (p = 0.007), and physical activity significantly varied between the groups (p = 0.0001). The study examined the predictors of comorbidity in Qatar as well as UK populations using multivariate logistic regression analysis. The result of the study showed no statistical association between comorbidity and the predictors drinking habit, smoking, physical activity, vegetable consumption, eat outs, and sleep perception for the Qatar population, and for the combined population. This study, however showed a significant association (p = 0.033) between sleep perception and comorbidity for the UK population. We conclude that further analysis is needed to understand the relationship between specific lifestyle factors and multimorbidity in each country.
Keywordsobesity; nutrition; depression; overweight; UK; Qatar
Year2023
JournalFrontiers in Public Health
Journal citation11, p. 1132994
PublisherFrontiers Media S.A.
ISSN2296-2565
Digital Object Identifier (DOI)https://doi.org/10.3389/fpubh.2023.1132994
Publication dates
Online03 May 2023
Publication process dates
Accepted13 Apr 2023
Deposited22 May 2023
Publisher's version
License
File Access Level
Open
Licensehttp://creativecommons.org/licenses/by/4.0/
Permalink -

https://openresearch.lsbu.ac.uk/item/94119

Download files


Publisher's version
fpubh-11-1132994.pdf
License: CC BY 4.0
File access level: Open

  • 60
    total views
  • 26
    total downloads
  • 2
    views this month
  • 3
    downloads this month

Export as

Related outputs

Nanoparticle mediated cancer cell therapy: Basic science to clinical applications
Verma, J., Warsame, C., Seenivasagam, R.K., Kumar, N., Abdel Aleem, E. and Goel, S. (2023). Nanoparticle mediated cancer cell therapy: Basic science to clinical applications. Cancer and Metastasis Reviews. https://doi.org/10.1007/s10555-023-10086-2
Exopolysaccharide-peptide complex from oyster mushroom (Pleurotus ostreatus) protects against hepatotoxicity in rats
Abdel-Monem, NM, El-Saadani, MA, Daba, AS, Saleh, SR and Aleem, E (2020). Exopolysaccharide-peptide complex from oyster mushroom (Pleurotus ostreatus) protects against hepatotoxicity in rats. Biochemistry and Biophysics Reports. 24, pp. 100852-100852. https://doi.org/10.1016/j.bbrep.2020.100852
Clinical resistance associated with a novel MAP2K1 mutation in a patient with Langerhans cell histiocytosis
Azorsa, DO, Lee, DW, Wai, DH, Bista, R, Patel, AR, Aleem, E, Henry, MM and Arceci, RJ (2018). Clinical resistance associated with a novel MAP2K1 mutation in a patient with Langerhans cell histiocytosis. Pediatric Blood and Cancer. 65 (9), pp. e27237-e27237. https://doi.org/10.1002/pbc.27237
Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells
Bista, R, Lee, DW, Pepper, OB, Azorsa, DO, Arceci, RJ and Aleem, E (2017). Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells. Journal of Experimental & Clinical Cancer Research. 36 (22). https://doi.org/10.1186/s13046-017-0493-5
Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage
Waraky, A, Lin, Y, Warsito, D, Haglund, F, Aleem, E and Larsson, O (2017). Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. Journal of Biological Chemistry. 292 (44), pp. 18227-18239. https://doi.org/10.1074/jbc.M117.781492
Downregulation of IGF-1 receptor occurs after hepatic linage commitment during hepatocyte differentiation from human embryonic stem cells
Waraky, A, Aleem, E and Larsson, O (2016). Downregulation of IGF-1 receptor occurs after hepatic linage commitment during hepatocyte differentiation from human embryonic stem cells. Biochemical and Biophysical Research Communications. 478 (4), pp. 1575-1581. https://doi.org/10.1016/j.bbrc.2016.08.157
Targeting cell cycle regulators in hematologic malignancies
Aleem, E. and Arceci, R.J. (2015). Targeting cell cycle regulators in hematologic malignancies. Frontiers in Cell and Developmental Biology. 3 (APR), pp. 16-. https://doi.org/10.3389/fcell.2015.00016
Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism
Waraky, A., Akopyan, K., Parrow, V., Strömberg, T., Axelson, M., Abrahmsén, L., Lindqvist, A., Larsson, O. and Aleem, E. (2014). Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism. Oncotarget. 5 (18), pp. 8379-8392. https://doi.org/10.18632/oncotarget.2292