MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.

Journal article


Lalla, RV, Bowen, J, Barasch, A, Elting, L, Epstein, J, Keefe, DM, McGuire, DB, Migliorati, C, Nicolatou-Galitis, O, Peterson, DE, Raber-Durlacher, JE, Sonis, ST and Elad, S (2014). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 120 (10), pp. 1453-1461.
AuthorsLalla, RV, Bowen, J, Barasch, A, Elting, L, Epstein, J, Keefe, DM, McGuire, DB, Migliorati, C, Nicolatou-Galitis, O, Peterson, DE, Raber-Durlacher, JE, Sonis, ST and Elad, S
Abstract

BACKGROUND: Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis. METHODS: A literature search was conducted to identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article was independently reviewed by 2 reviewers. Studies were rated according to the presence of major and minor flaws as per previously published criteria. The body of evidence for each intervention, in each treatment setting, was assigned a level of evidence, based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible. RESULTS: The literature search identified 8279 papers, 1032 of which were retrieved for detailed evaluation based on titles and abstracts. Of these, 570 qualified for final inclusion in the systematic reviews. Sixteen new guidelines were developed for or against the use of various interventions in specific treatment settings. In total, the MASCC/ISOO Mucositis Guidelines now include 32 guidelines: 22 for oral mucositis and 10 for gastrointestinal mucositis. This article describes these updated guidelines. CONCLUSIONS: The updated MASCC/ISOO Clinical Practice Guidelines for mucositis will help clinicians provide evidence-based management of mucositis secondary to cancer therapy.

Keywordsmucositis; stomatitis; oral; gastrointestinal; guidelines; Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC; ISOO); Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO); Humans; Neoplasms; Esophagitis; Proctitis; Stomatitis; Sucralfate; Amifostine; Intercellular Signaling Peptides and Proteins; Analgesics; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antineoplastic Agents; Cytokines; Protective Agents; Radiation-Protective Agents; Anti-Infective Agents; Oral Hygiene; Cryotherapy; Phototherapy; Laser Therapy, Low-Level; Radiotherapy; Hyperbaric Oxygenation; Evidence-Based Medicine; Mucositis; Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO); gastrointestinal; guidelines; mucositis; oral; stomatitis; Amifostine; Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antineoplastic Agents; Cryotherapy; Cytokines; Esophagitis; Evidence-Based Medicine; Humans; Hyperbaric Oxygenation; Intercellular Signaling Peptides and Proteins; Low-Level Light Therapy; Mucositis; Neoplasms; Oral Hygiene; Phototherapy; Proctitis; Protective Agents; Radiation-Protective Agents; Radiotherapy; Stomatitis; Sucralfate
Year2014
JournalCancer
Journal citation120 (10), pp. 1453-1461
PublisherLondon South Bank University
ISSN1097-0142
Digital Object Identifier (DOI)doi:10.1002/cncr.28592
Publication dates
Print15 May 2014
Publication process dates
Deposited28 Nov 2017
Accepted20 Dec 2013
Publisher's version
License
CC BY 4.0
ContributorsGibson, Faith
Permalink -

https://openresearch.lsbu.ac.uk/item/8782w

  • 2
    total views
  • 29
    total downloads
  • 0
    views this month
  • 3
    downloads this month