Dr Mohammed Mansour


NameDr Mohammed Mansour
Job titleLecturer
Organisational UnitHuman Sciences
ORCIDhttps://orcid.org/0000-0001-8701-4007

Research outputs

Dual inhibition of glycolysis and autophagy as a therapeutic strategy in the treatment of Ehrlich ascites carcinoma

Mansour, MA, Ibrahim, WM, Salama, MM and Salama, AF (2020). Dual inhibition of glycolysis and autophagy as a therapeutic strategy in the treatment of Ehrlich ascites carcinoma. Journal of Biochemical and Molecular Toxicology. 34 (7). https://doi.org/10.1002/jbt.22498

Assessment of Autophagy as Possible Mechanism of the Antitumor Effects of Arsenic Trioxide and/or Cisplatin on Ehrlich Ascites Carcinoma Model.

Mansour, M.A., Salama, A.F., Ibrahim, W.M. and Shalaan, E.S. (2019). Assessment of Autophagy as Possible Mechanism of the Antitumor Effects of Arsenic Trioxide and/or Cisplatin on Ehrlich Ascites Carcinoma Model. Alexandria Journal for Veterinary Sciences. 61 (1), pp. 159-167. https://doi.org/10.5455/ajvs.29544

Combination of arsenic trioxide and cisplatin synergistically inhibits both hexokinase activity and viability of Ehrlich ascites carcinoma cells

Mansour, Mohammed A, Ibrahim, Wafaa M, Shalaan, Eman S and Salama, Afrah F (2019). Combination of arsenic trioxide and cisplatin synergistically inhibits both hexokinase activity and viability of Ehrlich ascites carcinoma cells. Journal of biochemical and molecular toxicology. 33, pp. e22350-e22350. https://doi.org/10.1002/jbt.22350

Cisplatin augments the anti-schistosomal effect of praziquantel in a schistosoma-infected cancer model

Salem, M.L., Salama, A., El-Gowily, A.H., Mansour, M.A. and El-Said, M.M.A. (2019). Cisplatin augments the anti-schistosomal effect of praziquantel in a schistosoma-infected cancer model. Indian Journal of Biochemistry and Biophysics (IJBB). 56, pp. 57-69.

Pd (II) and Pt (II) chalcone complexes. Synthesis, spectral characterization, molecular modeling, biomolecular docking, antimicrobial and antitumor activities

Gaber, M., El-Ghamry, H.A and Mansour, M.A. (2018). Pd (II) and Pt (II) chalcone complexes. Synthesis, spectral characterization, molecular modeling, biomolecular docking, antimicrobial and antitumor activities. Journal of Photochemistry and Photobiology A: Chemistry. 354, pp. 163-174. https://doi.org/10.1016/j.jphotochem.2017.07.031

Nano-synthesis, characterization, modeling and molecular docking analysis of Mn (II), Co (II), Cr (III) and Cu (II) complexes with azo pyrazolone ligand as new favorable antimicrobial and antitumor agents

Gaber, M., Khedr, A.M., Mansour, M.A. and Elsharkawy, M. (2018). Nano-synthesis, characterization, modeling and molecular docking analysis of Mn (II), Co (II), Cr (III) and Cu (II) complexes with azo pyrazolone ligand as new favorable antimicrobial and antitumor agents. Applied Organometallic Chemistry. 32, pp. e4606-e4606. https://doi.org/10.1002/aoc.4606

Synthesis, spectroscopic, thermal and molecular modeling studies of Zn2+, Cd2+ and UO22+ complexes of Schiff bases containing triazole moiety. Antimicrobial, anticancer, antioxidant and DNA binding studies

Gaber, M., El-Ghamry, H.A., Fathalla, S.K. and Mansour, M.A. (2018). Synthesis, spectroscopic, thermal and molecular modeling studies of Zn2+, Cd2+ and UO22+ complexes of Schiff bases containing triazole moiety. Antimicrobial, anticancer, antioxidant and DNA binding studies. Materials Science and Engineering: C. 83, pp. 78-89. https://doi.org/10.1016/j.msec.2017.11.004

The phospholipid PI (3, 4) P 2 is an apical identity determinant

Román-Fernández, Á., Roignot, J., Sandilands, E., Nacke, M., Mansour, M.A., McGarry, L., Shanks, E., Mostov, K.E. and Bryant, D.M. (2018). The phospholipid PI (3, 4) P 2 is an apical identity determinant. Nature Communications. 9, pp. 1-17. https://doi.org/10.1038/s41467-018-07464-8

Ubiquitination: Friend and foe in cancer

Mansour, M.A. (2018). Ubiquitination: Friend and foe in cancer. The international journal of biochemistry & cell biology. 101, pp. 80-93. https://doi.org/10.1016/j.biocel.2018.06.001

FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression

Akter, K.A., Mansour, M.A., Hyodo, T. and Senga, T. (2017). FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression. The international journal of biochemistry & cell biology. 84, pp. 1-13. https://doi.org/10.1016/j.biocel.2016.12.013

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer

Mansour, M.A. and Senga, T. (2017). HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer. The international journal of biochemistry & cell biology. 88, pp. 1-13. https://doi.org/10.1016/j.biocel.2017.04.011

SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer

Mansour, MA, Hyodo, T, Akter, KA, Kokuryo, T, Uehara, K, Nagino, M and Senga, T (2016). SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer. Oncotarget. 7, pp. 4993-4993. https://doi.org/10.18632/oncotarget.6651

UBE2S is associated with malignant characteristics of breast cancer cells

Ayesha, A K, Hyodo, T, Asano, E, Sato, N, Mansour, M A, Ito, S, Hamaguchi, M and Senga, T (2016). UBE2S is associated with malignant characteristics of breast cancer cells. Tumor Biology. 37 (1), pp. 763-772. https://doi.org/10.1007/s13277-015-3863-7

FAM98A is a novel substrate of PRMT1 required for tumor cell migration, invasion, and colony formation

Akter, K.A., Mansour, M.A., Hyodo, T., Ito, S., Hamaguchi, M. and Senga, T. (2016). FAM98A is a novel substrate of PRMT1 required for tumor cell migration, invasion, and colony formation. Tumor Biology. 37, pp. 4531-4539. https://doi.org/10.1007/s13277-015-4310-5

TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion

Kurita, K, Maeda, M, Mansour, MA, Kokuryo, T, Uehara, K, Yokoyama, Y, Nagino, M, Hamaguchi, M and Senga, T (2016). TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion. Oncology letters. 12, pp. 5240-5246. https://doi.org/10.3892/ol.2016.5332

Special AT-rich sequence-binding protein 2 suppresses invadopodia formation in HCT116 cells via palladin inhibition

Mansour, M.A., Asano, E., Hyodo, T., Akter, K.A., Takahashi, M., Hamaguchi, M. and Senga, T. (2015). Special AT-rich sequence-binding protein 2 suppresses invadopodia formation in HCT116 cells via palladin inhibition. Experimental Cell Research. 332, pp. 78-88. https://doi.org/10.1016/j.yexcr.2014.12.003

SATB 2 suppresses the progression of colorectal cancer cells via inactivation of MEK 5/ERK 5 signaling

Mansour, M.A., Hyodo, T., Ito, S., Kurita, K., Kokuryo, T., Uehara, K., Nagino, M., Takahashi, M., Hamaguchi, M. and Senga, T. (2015). SATB 2 suppresses the progression of colorectal cancer cells via inactivation of MEK 5/ERK 5 signaling. The FEBS journal. 282 (8), pp. 1394-1405. https://doi.org/10.1111/febs.13227

Treatment with folic acid ameliorated the histopathological alterations caused by propylthiouracil-induced hypothyroid rat testes

Tousson, E., Ali, E.M.M., Ibrahim, W. and Mansour, M.A. (2012). Treatment with folic acid ameliorated the histopathological alterations caused by propylthiouracil-induced hypothyroid rat testes. Toxicology and industrial health. 28 (6), pp. 566-576. https://doi.org/10.1177/0748233711420469

Folic acid alleviates oxidative stress and hyperhomocysteinemia involved in testicular dysfunction of hypothyroid rats

Ibrahim, W., Tousson, E., Ali, E.M.M. and Mansour, M.A. (2011). Folic acid alleviates oxidative stress and hyperhomocysteinemia involved in testicular dysfunction of hypothyroid rats. General and comparative endocrinology. 174, pp. 143-149. https://doi.org/10.1016/j.ygcen.2011.08.012

Proliferating cell nuclear antigen as a molecular biomarker for spermatogenesis in PTU-induced hypothyroidism of rats

Tousson, E., Ali, E.M.M., Ibrahim, W. and Mansour, M.A. (2011). Proliferating cell nuclear antigen as a molecular biomarker for spermatogenesis in PTU-induced hypothyroidism of rats. Reproductive sciences. 18, pp. 679-686. https://doi.org/10.1177/1933719110395401

Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells.

El-Gowily, A.H., Loutfy, S.A., Ali, E., Mohamed, T. and Mansour, M. (2021). Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. Pharmaceuticals. 14 (3). https://doi.org/ph14030254

SP3 is associated with migration, invasion, and Akt/PKB signalling in MDA‐MB‐231 breast cancer cells

Mansour, M. (2020). SP3 is associated with migration, invasion, and Akt/PKB signalling in MDA‐MB‐231 breast cancer cells. Journal of biochemical and molecular toxicology. 35 (3). https://doi.org/10.1002/jbt.22657
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