Two Stage Sub-Wavelength Motion Correction in Human Microvasculature for CEUS Imaging

Conference paper

Harput, S., Christensen-Jeffries, K, Li, Y., Brown, J., Eckersley, R.J., Dunsby, C. and Tang, M-X. (2017). Two Stage Sub-Wavelength Motion Correction in Human Microvasculature for CEUS Imaging. 2017 IEEE International Ultrasonics Symposium (IUS). Washington, DC, USA 06 - 09 Sep 2019 Institute of Electrical and Electronics Engineers (IEEE). doi:10.1109/ULTSYM.2017.8092538
AuthorsHarput, S., Christensen-Jeffries, K, Li, Y., Brown, J., Eckersley, R.J., Dunsby, C. and Tang, M-X.
TypeConference paper
Abstract

The structure of microvasculature cannot be resolved using clinical B-mode or contrast-enhanced ultrasound (CEUS) imaging due to the fundamental diffraction limit at clinical ultrasound frequencies. It is possible to overcome this resolution limitation by localizing individual microbubbles through multiple frames and forming a super-resolved image. However, ultrasound super-resolution creates its unique problems since the structures to be imaged are on the order of 10s of μm. Tissue movement much larger than 10 μm is common in clinical imaging, which can significantly reduce the accuracy of super-resolution images created from microbubble locations gathered through hundreds of frames. This study investigated an existing motion estimation algorithm from magnetic resonance imaging for ultrasound super-resolution imaging. Its correction accuracy is evaluated using simulations with increasing complexity of motion. Feasibility of the method for ultrasound super-resolution in vivo is demonstrated on clinical ultrasound images. For a chosen microvessel, the super-resolution image without motion correction achieved a sub-wavelength resolution; however after the application of proposed two-stage motion correction method the size of the vessel was reduced to half.

© 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

Year2017
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
ISSN1948-5727
Digital Object Identifier (DOI)doi:10.1109/ULTSYM.2017.8092538
Web address (URL)https://ieeexplore.ieee.org/document/8092538
Accepted author manuscript
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Open
Publication dates
Online02 Nov 2017
Publication process dates
Accepted01 Sep 2017
Deposited12 Aug 2019
ISBN978-1-5386-3383-0
Web address (URL) of conference proceedingshttps://ieeexplore.ieee.org/xpl/conhome/8081728/proceeding
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