Participant number
Order of nicotine e-liquid
In years
Male/Female
Ethnicity
Occupation
Qualification
Age started smoking
Time (in months) since quit smoking
Cigarettes per day
Method used to stop smoking
How addicted were you to smoking? (0-100%)
What did you smoke?
How soon did you used to smoke your first cigarette of the day?
E-liquid flavour chosen for study
Type of e-cigarette currently used
Baseline battery used
Baseline Voltage used
Baseline Wattage used
Baseline Tank used
Baseline Atomiser used
Baseline atomiser resistance used
Baseline strenth of nicotine used
Baseline estimated puffs per day
Baseline estimated mL of e-liquid used per day
Baseline preferred flavour
Baseline CO level
Baseline saliva cotinine in ng/mL
Baseline Salivary cotinine to 3-hydroxy cotinine ratio
6 Fixed saliva cotinine
18 Fixed saliva cotinine
6 Adjustable saliva cotinine
18 Adjustable saliva cotinine
6 Fixed mean daily mL liquid consumed
18 Fixed mean daily mL liquid consumed
6 Adjustable mean daily mL liquid consumed
18 Adjustable mean daily mL liquid consumed
6 Fixed CO level
18 Fixed CO level
6 Adjustable CO level
18 Adjustable CO level
How soon after waking do you take your first e-cig puff?
Do you find it difficult to refrain for e-cig use in places where forbidden?
Which e-cig puffs would you hate most to give up?
Do you puff more frequently during the first hours of waking?
Do you vape if you are so ill you are in bed most of the day?
Self-rated addiction to e-cigarettes (0-100%)
For you, stopping vaping completely would be...
Penn State E-cig index - puffs per day
Penn State E-cig index how soon after waking (in minutes)
Penn State E-cig index awaken to use
Penn State E-cig index -if yes to awaken, how often
Penn State E-cig index - would it be hard to quit
Penn State E-cig index - craving
Penn State E-cig index urge
Penn State E-cig index able to refrain
Penn State E-cig index irritible when not using
Penn State E-cig index anxiety
Total Penn State score
Mood and physical symptom scales depressed
Mood and physical symptom scales irritable
Mood and physical symptom scales anxious
Mood and physical symptom scales restless
Mood and physical symptom scales hungry
Mood and physical symptom scales concentrate
Mood and physical symptom scale total score
Baseline Urge to vape in the past week
Baseline Urge to vape - strength of urges
Subjective effects throat hit (VAS 0-200mm)
Subjective effects satisying (VAS 0-200mm)
Subjective effects pleasant (VAS 0-200mm)
Subjective effects tastes good (VAS 0-200mm)
Subjective effects reduced craving (VAS 0-200mm)
Subjective effects helped concentration (VAS 0-200mm)
Subjective effects has made me feel calmer (VAS 0-200mm)
Subjective effects made me feel more awake (VAS 0-200mm)
Subjective effects reduced my hunger (VAS 0-200mm)
Subjective effects tastes like my usual brand (VAS 0-200mm)
Subjective effects feels like my usual brand (VAS 0-200mm)
Subjective effects nicotine hit (VAS 0-200mm)
Subjective effects burning sensation (VAS 0-200mm)
Subjective effects horrible taste (VAS 0-200mm)
Adverse effects confused (VAS 0-200mm)
Adverse effects dizzy (VAS 0-200mm)
Adverse effects headache (VAS 0-200mm)
Adverse effects pounding heart (VAS 0-200mm)
Adverse effects light-headed (VAS 0-200mm)
Adverse effects nausea (VAS 0-200mm)
Adverse effects nervous (VAS 0-200mm)
Adverse effects salivation (VAS 0-200mm)
Adverse effects sweaty (VAS 0-200mm)
Adverse effects weak (VAS 0-200mm)
Adverse effects mouth irritation (VAS 0-200mm)
Adverse effects throat irritation (VAS 0-200mm)
Adverse effects aching jaws (VAS 0-200mm)
Adverse effects vomiting (VAS 0-200mm)
Adverse effects bloating (VAS 0-200mm)
Adverse effects stomach ache (VAS 0-200mm)
Adverse effects heart-burn (VAS 0-200mm)
Adverse effects diarrhoea (VAS 0-200mm)
Adverse effects hiccups (VAS 0-200mm)
Adverse effects cold hand or feet (VAS 0-200mm)
Adverse effects palpitations (VAS 0-200mm)
6 Fixed condition: MPSS Depressed
6 Fixed condition: MPSS Irritable
6 Fixed condition: MPSS Anxious
6 Fixed condition: MPSS Restless
6 Fixed condition: MPSS Hungry
6 Fixed condition: MPSS Unable to concentrate
6 Fixed condition: MPSS total score
6 Fixed urge to vape in the past week
6 Fixed strength of urges
6 Fixed Subjective effects throat hit (VAS 0-200mm)
6 Fixed Subjective effects satisying (VAS 0-200mm)
6 Fixed Subjective effects pleasant (VAS 0-200mm)
6 Fixed Subjective effects tastes good (VAS 0-200mm)
6 Fixed Subjective effects reduced craving (VAS 0-200mm)
6 Fixed Subjective effects helped concentration (VAS 0-200mm)
6 Fixed Subjective effects has made me feel calmer (VAS 0-200mm)
6 Fixed Subjective effects made me feel more awake (VAS 0-200mm)
6 Fixed Subjective effects reduced my hunger (VAS 0-200mm)
6 Fixed Subjective effects tastes like my usual brand (VAS 0-200mm)
6 Fixed Subjective effects feels like my usual brand (VAS 0-200mm)
6 Fixed Subjective effects nicotine hit (VAS 0-200mm)
6 Fixed Subjective effects burning sensation (VAS 0-200mm)
6 Fixed Subjective effects horrible taste (VAS 0-200mm)
6 Fixed Adverse effects confused (VAS 0-200mm)
6 Fixed Adverse effects dizzy (VAS 0-200mm)
6 Fixed Adverse effects headache (VAS 0-200mm)
6 Fixed Adverse effects pounding heart (VAS 0-200mm)
6 Fixed Adverse effects light-headed (VAS 0-200mm)
6 Fixed Adverse effects nausea (VAS 0-200mm)
6 Fixed Adverse effects nervous (VAS 0-200mm)
6 Fixed Adverse effects salivation (VAS 0-200mm)
6 Fixed Adverse effects sweaty (VAS 0-200mm)
6 Fixed Adverse effects weak (VAS 0-200mm)
6 Fixed Adverse effects mouth irritation (VAS 0-200mm)
6 Fixed Adverse effects throat irritation (VAS 0-200mm)
6 Fixed Adverse effects aching jaws (VAS 0-200mm)
6 Fixed Adverse effects vomiting (VAS 0-200mm)
6 Fixed Adverse effects bloating (VAS 0-200mm)
6 fixed Adverse effects stomach ache (VAS 0-200mm)
6 fixed Adverse effects heart-burn (VAS 0-200mm)
6 Fixed Adverse effects diarrhoea (VAS 0-200mm)
6 Fixed Adverse effects hiccups (VAS 0-200mm)
6 Fixed Adverse effects cold hand or feet (VAS 0-200mm)
6 Fixed Adverse effects palpitations (VAS 0-200mm)
18 Fixed Mood and physical symptom scales depressed
18 Fixed Mood and physical symptom scales irritable
18 Fixed Mood and physical symptom scales anxious
18 Fixed Mood and physical symptom scales restless
18 Fixed Mood and physical symptom scales hungry
18 Fixed Mood and physical symptom scales concentrate
18 Fixed Mood and physical symptom scale total score
18 Fixed urge to vape in the past week
18 Fixed strength of urges
18 Fixed Subjective effects throat hit (VAS 0-200mm)
18 Fixed Subjective effects satisying (VAS 0-200mm)
18 Fixed Subjective effects pleasant (VAS 0-200mm)
18 Fixed Subjective effects tastes good (VAS 0-200mm)
18 Fixed Subjective effects reduced craving (VAS 0-200mm)
18 Fixed Subjective effects helped concentration (VAS 0-200mm)
18 Fixed Subjective effects has made me feel calmer (VAS 0-200mm)
18 Fixed Subjective effects made me feel more awake (VAS 0-200mm)
18 Fixed Subjective effects reduced my hunger (VAS 0-200mm)
18 Fixed Subjective effects tastes like my usual brand (VAS 0-200mm)
18 Fixed Subjective effects feels like my usual brand (VAS 0-200mm)
18 Fixed Subjective effects nicotine hit (VAS 0-200mm)
18 Fixed Subjective effects burning sensation (VAS 0-200mm)
18 Fixed Subjective effects horrible taste (VAS 0-200mm)
18 Fixed Adverse effects confused (VAS 0-200mm)
18 Fixed Adverse effects dizzy (VAS 0-200mm)
18 Fixed Adverse effects headache (VAS 0-200mm)
18 Fixed Adverse effects pounding heart (VAS 0-200mm)
18 Fixed Adverse effects light-headed (VAS 0-200mm)
18 Fixed Adverse effects nausea (VAS 0-200mm)
18 Fixed Adverse effects nervous (VAS 0-200mm)
18 Fixed Adverse effects salivation (VAS 0-200mm)
18 Fixed Adverse effects sweaty (VAS 0-200mm)
18 Fixed Adverse effects weak (VAS 0-200mm)
18 Fixed Adverse effects mouth irritation (VAS 0-200mm)
18 Fixed Adverse effects throat irritation (VAS 0-200mm)
18 Fixed Adverse effects aching jaws (VAS 0-200mm)
18 Fixed Adverse effects vomiting (VAS 0-200mm)
18 Fixed Adverse effects bloating (VAS 0-200mm)
18 fixed Adverse effects stomach ache (VAS 0-200mm)
18 fixed Adverse effects heart-burn (VAS 0-200mm)
18 Fixed Adverse effects diarrhoea (VAS 0-200mm)
18 Fixed Adverse effects hiccups (VAS 0-200mm)
18 Fixed Adverse effects cold hand or feet (VAS 0-200mm)
18 Fixed Adverse effects palpitations (VAS 0-200mm)
6 Adjustable condition: MPSS Depressed
6 Adjustable condition: MPSS Irritable
6 Adjustable condition: MPSS Anxious
6 Adjustable condition: MPSS Restless
6 Adjustable condition: MPSS Hungry
6 Adjustable condition: MPSS Unable to concentrate
6 Adjustable condition: MPSS total score
6 Adjustable urge to vape in the past week
6 Adjustable strength of urges
6 Adjustable Subjective effects throat hit (VAS 0-200mm)
6 Adjustable Subjective effects satisying (VAS 0-200mm)
6 Adjustable Subjective effects pleasant (VAS 0-200mm)
6 Adjustable Subjective effects tastes good (VAS 0-200mm)
6 Adjustable Subjective effects reduced craving (VAS 0-200mm)
6 Adjustable Subjective effects helped concentration (VAS 0-200mm)
6 Adjustable Subjective effects has made me feel calmer (VAS 0-200mm)
6 Adjustable Subjective effects made me feel more awake (VAS 0-200mm)
6 Adjustable Subjective effects reduced my hunger (VAS 0-200mm)
6 Adjustable Subjective effects tastes like my usual brand (VAS 0-200mm)
6 Adjustable Subjective effects feels like my usual brand (VAS 0-200mm)
6 Adjustable Subjective effects nicotine hit (VAS 0-200mm)
6 Adjustable Subjective effects burning sensation (VAS 0-200mm)
6 Adjustable Subjective effects horrible taste (VAS 0-200mm)
6 Adjustable Adverse effects confused (VAS 0-200mm)
6 Adjustable Adverse effects dizzy (VAS 0-200mm)
6 Adjustable Adverse effects headache (VAS 0-200mm)
6 Adjustable Adverse effects pounding heart (VAS 0-200mm)
6 Adjustable Adverse effects light-headed (VAS 0-200mm)
6 Adjustable Adverse effects nausea (VAS 0-200mm)
6 Adjustable Adverse effects nervous (VAS 0-200mm)
6 Adjustable Adverse effects salivation (VAS 0-200mm)
6 Adjustable Adverse effects sweaty (VAS 0-200mm)
6 Adjustable Adverse effects weak (VAS 0-200mm)
6 Adjustable Adverse effects mouth irritation (VAS 0-200mm)
6 Adjustable Adverse effects throat irritation (VAS 0-200mm)
6 Adjustable Adverse effects aching jaws (VAS 0-200mm)
6 Adjustable Adverse effects vomiting (VAS 0-200mm)
6 Adjustable Adverse effects bloating (VAS 0-200mm)
6 Adjustable Adverse effects stomach ache (VAS 0-200mm)
6 Adjustable Adverse effects heart-burn (VAS 0-200mm)
6 Adjustable Adverse effects diarrhoea (VAS 0-200mm)
6 Adjustable Adverse effects hiccups (VAS 0-200mm)
6 Adjustable Adverse effects cold hand or feet (VAS 0-200mm)
6 Adjustable Adverse effects palpitations (VAS 0-200mm)
18 Adjustable Mood and physical symptom scales depressed
18 Adjustable Mood and physical symptom scales irritable
18 Adjustable Mood and physical symptom scales anxious
18 Adjustable Mood and physical symptom scales restless
18 Adjustable Mood and physical symptom scales hungry
18 Adjustable Mood and physical symptom scales concentrate
18 Adjustable Mood and physical symptom scale total score
18 Adjustable urge to vape in the past week
18 Adjustable strength of urges
18 Adjustable Adverse effects confused (VAS 0-200mm)
18 Adjustable Adverse effects dizzy (VAS 0-200mm)
18 Adjustable Adverse effects headache (VAS 0-200mm)
18 Adjustable Adverse effects pounding heart (VAS 0-200mm)
18 Adjustable Adverse effects light-headed (VAS 0-200mm)
18 Adjustable Adverse effects nausea (VAS 0-200mm)
18 Adjustable Adverse effects nervous (VAS 0-200mm)
18 Adjustable Adverse effects salivation (VAS 0-200mm)
18 Adjustable Adverse effects sweaty (VAS 0-200mm)
18 Adjustable Adverse effects weak (VAS 0-200mm)
18 Adjustable Adverse effects mouth irritation (VAS 0-200mm)
18 Adjustable Adverse effects throat irritation (VAS 0-200mm)
18 Adjustable Adverse effects aching jaws (VAS 0-200mm)
18 Adjustable Adverse effects vomiting (VAS 0-200mm)
18 Adjustable Adverse effects bloating (VAS 0-200mm)
18 Adjustable Adverse effects stomach ache (VAS 0-200mm)
18 Adjustable Adverse effects heart-burn (VAS 0-200mm)
18 Adjustable Adverse effects diarrhoea (VAS 0-200mm)
18 Adjustable Adverse effects hiccups (VAS 0-200mm)
18 Adjustable Adverse effects cold hand or feet (VAS 0-200mm)
18 Adjustable Adverse effects palpitations (VAS 0-200mm)
6 Fixed total (average percentage) adverse effects score
18 Fixed total (average percentage) subjective effects score (excl burning & horrible taste)
18 Fixed total (average percentage) adverse effects score
6 Adjustable total (average percentage) subjective effects score (excl burning & horrible taste)
6 Adjustable total (average percentage) adverse effects score
18 Adjustable total (average percentage) subjective effects score (excl burning & horrible taste)
18 Adjustable total (average percentage) adverse effects score
6 Fixed Average puff duration (in seconds)
18 Fixed Average puff duration (in seconds)
6 Adjustable Average puff duration (in seconds)
18 Adjustable Average puff duration (in seconds)
6 Fixed Average Inter-puff-interval
18 Fixed Average Inter-puff-interval
6 Adjustable Average Inter-puff-interval
18 Adjustable Average Inter-puff-interval
6 Fixed Average Voltage
18 Fixed Average Voltage
6 Adjustable Average Voltage
18 Adjustable Average Voltage
Categorical variable to represent whether user increased or decreased voltage with 6mg nicotine
Categorical variable to represent whether user increased or decreased voltage with 18mg nicotine
mean number of puffs per day 6 fixed (with 1st and last day removed)
mean number of puffs per day 18 fixed (with 1st and last day removed)
mean number of puffs per day 6 adjustable (with 1st and last day removed)
mean number of puffs per day 18 adjustable (with 1st and last day removed)
6 Fixed total (average percentage) subjective (positive) effects score (excl burning & horrible taste)
18 Fixed total (average percentage) subjective (positive) effects score (excl burning & horrible taste)
6 Adjustable total (average percentage) subjective (positive) effects score (excl burning & horrible taste)
18 Adjustable total (average percentage) subjective (positive) effects score (excl burning & horrible taste)
6 Fixed Nicotine hit percentage score (original score/2)
18 Fixed Nicotine hit percentage score (original score/2)
6 Adjustable Nicotine hit percentage score (original score/2)
18 Adjustable Nicotine hit percentage score (original score/2)
6 Fixed Throat hit percentage score (original score/2)
18 Fixed Throat hit percentage score (original score/2)
6 Adjustable Throat hit percentage score (original score/2)
18 Adjustable Throat hit percentage score (original score/2)
6 Fixed satisfaction percentage score (original score/2)
18 Fixed satisfaction percentage score (original score/2)
6 Adjustable satisfaction percentage score (original score/2)
18 Adjustable satisfaction percentage score (original score/2)
Baseline 3-HPMA (creatinine adjusted)
Baseline formate (creatinine adjusted)
6 Fixed 3-HPMA (creatinine adjusted)
6 Fixed formate (creatinine adjusted)
18 Fixed 3-HPMA (creatinine adjusted)
18 Fixed formate (creatinine adjusted)
6 Adjustable 3-HPMA (creatinine adjusted)
6 Adjustable formate (creatinine adjusted)
18 Adjustable 3-HPMA (creatinine adjusted)